[4-[3-[(2-chloro-4-pyrimidinyl)amino]phenoxy]butyl]-carbamic acid 1,1-dimethylethylester

Base Information

Chemical Name:[4-[3-[(2-chloro-4-pyrimidinyl)amino]phenoxy]butyl]-carbamic acid 1,1-dimethylethylester
CAS No.:892413-74-0
Molecular Formula:C₁₉H₂₅ClN₄O₃
Molecular Weight:392.885
Hs Code.:

Synonyms:[4-[3-[(2-chloro-4-pyrimidinyl)amino]phenoxy]butyl]-carbamic acid 1,1-dimethylethylester

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Chemical Property of [4-[3-[(2-chloro-4-pyrimidinyl)amino]phenoxy]butyl]-carbamic acid 1,1-dimethylethylester

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Technology Process of [4-[3-[(2-chloro-4-pyrimidinyl)amino]phenoxy]butyl]-carbamic acid 1,1-dimethylethylester

There total 1 articles about [4-[3-[(2-chloro-4-pyrimidinyl)amino]phenoxy]butyl]-carbamic acid 1,1-dimethylethylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.3%

: 3934-20-1
2,6-Dichloropyrimidine

: 892413-73-9
[4-(3-aminophenoxy)butyl]-carbamic acid 1,1-dimethylethyl ester

: 892413-74-0
[4-[3-[(2-chloro-4-pyrimidinyl)amino]phenoxy]butyl]-carbamic acid 1,1-dimethylethylester

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In ethanol; for 20h; Heating / reflux;

Reference yield: 100.0%

: 892413-74-0
[4-[3-[(2-chloro-4-pyrimidinyl)amino]phenoxy]butyl]-carbamic acid 1,1-dimethylethylester

: 138563-68-5
tert-butyl (3-amino-phenoxy)-acetate

: 892413-75-1
[3-[[4-[[3-(4-aminobutoxy)phenyl]amino]-2-pyrimidinyl]amino]phenoxy]-acetic acid

Guidance literature:: [4-[3-[(2-chloro-4-pyrimidinyl)amino]phenoxy]butyl]-carbamic acid 1,1-dimethylethylester; tert-butyl (3-amino-phenoxy)-acetate; With hydrogenchloride; water; isopropyl alcohol; pH=7; Heating / reflux;

With sodium hydroxide; In water; for 20h; Heating / reflux;