5-(4-Methoxybenzyl)-2-furoic acid

Base Information

Chemical Name:5-(4-Methoxybenzyl)-2-furoic acid
CAS No.:3988-92-9
Molecular Formula:C₁₃H₁₂O₄
Molecular Weight:232.236
Hs Code.:
DSSTox Substance ID:DTXSID201226794

Synonyms:5-(4-Methoxybenzyl)-2-furoic acid;3988-92-9;5-(4-Methoxybenzyl)furan-2-carboxylic acid;5-[(4-Methoxyphenyl)methyl]furan-2-carboxylic acid;DTXSID201226794;5-[(4-Methoxyphenyl)methyl]-2-furancarboxylic acid

Suppliers and Price of 5-(4-Methoxybenzyl)-2-furoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-(4-Methoxybenzyl)-2-furoic acid

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:232.07355886
Heavy Atom Count:17
Complexity:258

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=C(C=C1)CC2=CC=C(O2)C(=O)O

Technology Process of 5-(4-Methoxybenzyl)-2-furoic acid

There total 3 articles about 5-(4-Methoxybenzyl)-2-furoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 15045-67-7
methyl 5-(4-methoxybenzyl)furan-2-carboxylate

: 3988-92-9
5-p-Methoxybenzyl-2-furancarbonsaeure

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; water; at 20 ℃;
DOI:10.1021/acs.joc.6b01774

Reference yield:

: 65650-04-6
5-(4-methoxy-benzoyl)-furan-2-carboxylic acid methyl ester

: 3988-92-9
5-p-Methoxybenzyl-2-furancarbonsaeure

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium tetrahydroborate / methanol / 1 h / 0 °C

1.2: 0.5 h / 0 °C

2.1: sodium hydroxide / tetrahydrofuran; water / 20 °C

With sodium tetrahydroborate; sodium hydroxide; In tetrahydrofuran; methanol; water;
DOI:10.1021/acs.joc.6b01774