methyl 2,3-di-O-benzoyl-4,6-O-((R)-1-methoxycarbonylethylidene)-β-D-galactopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl-(1->3) 2,4-di-O-benzyl-β-L-fucopyranoside

Base Information

Chemical Name:methyl 2,3-di-O-benzoyl-4,6-O-((R)-1-methoxycarbonylethylidene)-β-D-galactopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl-(1->3) 2,4-di-O-benzyl-β-L-fucopyranoside
CAS No.:208644-74-0
Molecular Formula:C₇₃H₇₃NO₂₀
Molecular Weight:1284.38
Hs Code.:

methyl 2,3-di-O-benzoyl-4,6-O-((R)-1-methoxycarbonylethylidene)-β-D-galactopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl-(1->3) 2,4-di-O-benzyl-β-L-fucopyranoside

Synonyms:methyl 2,3-di-O-benzoyl-4,6-O-((R)-1-methoxycarbonylethylidene)-β-D-galactopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl-(1->3) 2,4-di-O-benzyl-β-L-fucopyranoside

Suppliers and Price of methyl 2,3-di-O-benzoyl-4,6-O-((R)-1-methoxycarbonylethylidene)-β-D-galactopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl-(1->3) 2,4-di-O-benzyl-β-L-fucopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 2,3-di-O-benzoyl-4,6-O-((R)-1-methoxycarbonylethylidene)-β-D-galactopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl-(1->3) 2,4-di-O-benzyl-β-L-fucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 2,3-di-O-benzoyl-4,6-O-((R)-1-methoxycarbonylethylidene)-β-D-galactopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl-(1->3) 2,4-di-O-benzyl-β-L-fucopyranoside

There total 14 articles about methyl 2,3-di-O-benzoyl-4,6-O-((R)-1-methoxycarbonylethylidene)-β-D-galactopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl-(1->3) 2,4-di-O-benzyl-β-L-fucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 138857-83-7
phenyl 4,6-O-[1-(R)-(methoxycarbonyl)ethylidene]-2,3-di-O-benzoyl-1-thio-β-D-galactopyranoside

: 208644-73-9
methyl 2,4-di-O-benzyl-3-O-(3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl)-β-L-fucopyranoside

: 208644-74-0
methyl 2,3-di-O-benzoyl-4,6-O-((R)-1-methoxycarbonylethylidene)-β-D-galactopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl-(1->3) 2,4-di-O-benzyl-β-L-fucopyranoside

Guidance literature:: With N-iodo-succinimide; 4 A molecular sieve; silver trifluoromethanesulfonate; In dichloromethane; toluene; at -20 ℃; for 0.5h;
DOI:10.1080/07328309808002904

Reference yield:

: 10022-13-6
1,3,4,6-tetra-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranose

: 208644-74-0
methyl 2,3-di-O-benzoyl-4,6-O-((R)-1-methoxycarbonylethylidene)-β-D-galactopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl-(1->3) 2,4-di-O-benzyl-β-L-fucopyranoside

Guidance literature:: Multi-step reaction with 9 steps

1: 75 percent / BF₃*OEt₂ / CH₂Cl₂ / 15 h / Ambient temperature

2: NaOMe / methanol; CH₂Cl₂ / 2 h / Ambient temperature

3: TsOH*H₂O / acetonitrile / 15 h / Ambient temperature

4: 1.) NaH / 1) DMF, 0 deg C, 30 min; 2) DMF, rt, overnight

5: 100 percent / 4 Angstroem MS, NaBH₃CN / tetrahydrofuran / Ambient temperature

6: 100 percent / pyridine / Ambient temperature

7: 72 percent / 4 Angstroem molecular sieves, NIS, AgOTf / CH₂Cl₂; toluene / 0.25 h / -30 °C

8: 100 percent / NaOMe / methanol; CH₂Cl₂ / 1 h / Ambient temperature

9: 71 percent / 4 Angstroem, NIS, AgOTf / CH₂Cl₂; toluene / 0.5 h / -20 °C

With pyridine; N-iodo-succinimide; 4 A molecular sieve; 4 Angstroem MS; boron trifluoride diethyl etherate; sodium methylate; silver trifluoromethanesulfonate; sodium hydride; sodium cyanoborohydride; toluene-4-sulfonic acid; In tetrahydrofuran; methanol; dichloromethane; toluene; acetonitrile;
DOI:10.1080/07328309808002904

Reference yield:

: 16758-34-2
1-thiophenyl-β-D-galactopyranoside

: 208644-74-0
methyl 2,3-di-O-benzoyl-4,6-O-((R)-1-methoxycarbonylethylidene)-β-D-galactopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl-(1->3) 2,4-di-O-benzyl-β-L-fucopyranoside

Guidance literature:: Multi-step reaction with 5 steps

1: camphorsulfonic acid / dimethylformamide / 2 h / 50 °C

2: 90 percent / pyridine

3: 80 percent / aq. HOAc

4: 64 percent / BF₃*OEt₂ / acetonitrile / Ambient temperature

5: 71 percent / 4 Angstroem, NIS, AgOTf / CH₂Cl₂; toluene / 0.5 h / -20 °C

With pyridine; N-iodo-succinimide; 4 A molecular sieve; camphor-10-sulfonic acid; boron trifluoride diethyl etherate; silver trifluoromethanesulfonate; acetic acid; In dichloromethane; N,N-dimethyl-formamide; toluene; acetonitrile;
DOI:10.1080/07328309808002904