C₄₉H₆₇N₇O₉Si

Base Information

• Chemical Name: C₄₉H₆₇N₇O₉Si
• CAS No.: 295782-17-1
• Molecular Formula: C₄₉H₆₇N₇O₉Si
• Molecular Weight: 926.198
• Mol file: 295782-17-1.mol

Synonyms:C₄₉H₆₇N₇O₉Si

Chemical Property of C₄₉H₆₇N₇O₉Si

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of C₄₉H₆₇N₇O₉Si

There total 4 articles about C₄₉H₆₇N₇O₉Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

6,7-Bis-bromomethyl-1,4-dihydro-phthalazine-2,3-dicarboxylic acid di-tert-butyl ester (173723-91-6) + C29H41N5O5Si (295362-51-5) → C49H67N7O9Si (295782-17-1)

Guidance literature:

With sodium hydride; In tetrahydrofuran; dimethyl sulfoxide;

DOI:10.1021/ja0016304

Reference yield:

triisopropylsilyl trifluoromethanesulfonate (80522-42-5) → C49H67N7O9Si (295782-17-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 53 percent / 2,6-lutidine / CH₂Cl₂

2: 67 percent / NaH / dimethylsulfoxide; tetrahydrofuran

With 2,6-dimethylpyridine; sodium hydride; In tetrahydrofuran; dichloromethane; dimethyl sulfoxide;

DOI:10.1021/ja0016304

Reference yield:

(1R,2R,6S,7S)-9,9-Dihydroxy-4-((R)-2-hydroxy-1-phenyl-ethyl)-4-aza-tricyclo[5.2.2.02,6]undecane-3,5,8-trione → C49H67N7O9Si (295782-17-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 50 percent / TFA / toluene

2: 53 percent / 2,6-lutidine / CH₂Cl₂

3: 67 percent / NaH / dimethylsulfoxide; tetrahydrofuran

With 2,6-dimethylpyridine; sodium hydride; trifluoroacetic acid; In tetrahydrofuran; dichloromethane; dimethyl sulfoxide; toluene;

DOI:10.1021/ja0016304

upstream raw materials:

6,7-Bis-bromomethyl-1,4-dihydro-phthalazine-2,3-dicarboxylic acid di-tert-butyl ester

C₂₉H₄₁N₅O₅Si

triisopropylsilyl trifluoromethanesulfonate

C₂₀H₂₁N₅O₅