N₁,N₃-bis[(1R,2R)-2-((4-trifluoromethylphenyl)sulfonamido)cyclohexyl]benzene-1,3-disulfonamide

Base Information

• Chemical Name: N₁,N₃-bis[(1R,2R)-2-((4-trifluoromethylphenyl)sulfonamido)cyclohexyl]benzene-1,3-disulfonamide
• CAS No.: 1268855-63-5
• Molecular Formula: C₃₂H₃₆F₆N₄O₈S₄
• Molecular Weight: 846.914

Synonyms:N₁,N₃-bis[(1R,2R)-2-((4-trifluoromethylphenyl)sulfonamido)cyclohexyl]benzene-1,3-disulfonamide

Chemical Property of N₁,N₃-bis[(1R,2R)-2-((4-trifluoromethylphenyl)sulfonamido)cyclohexyl]benzene-1,3-disulfonamide

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Technology Process of N₁,N₃-bis[(1R,2R)-2-((4-trifluoromethylphenyl)sulfonamido)cyclohexyl]benzene-1,3-disulfonamide

There total 1 articles about N₁,N₃-bis[(1R,2R)-2-((4-trifluoromethylphenyl)sulfonamido)cyclohexyl]benzene-1,3-disulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

N-(1R,2R)-(2-aminocyclohexyl)-4-(trifluoromethyl)benzenesulfonamide (936110-78-0) + benzene-1,3-disulfonyl chloride (585-47-7) → N1,N3-bis[(1R,2R)-2-((4-trifluoromethylphenyl)sulfonamido)cyclohexyl]benzene-1,3-disulfonamide (1268855-63-5)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃;

DOI:10.1016/j.tetasy.2010.11.023

upstream raw materials:

N-(1R,2R)-(2-aminocyclohexyl)-4-(trifluoromethyl)benzenesulfonamide

benzene-1,3-disulfonyl chloride

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