N2-isobutyryl-9-[3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-β-D-arabinofuranosyl]guanine

Base Information

Chemical Name:N2-isobutyryl-9-[3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-β-D-arabinofuranosyl]guanine
CAS No.:160684-47-9
Molecular Formula:C₂₆H₄₅N₅O₇Si₂
Molecular Weight:595.844
Hs Code.:

Synonyms:N2-isobutyryl-9-[3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-β-D-arabinofuranosyl]guanine

Suppliers and Price of N2-isobutyryl-9-[3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-β-D-arabinofuranosyl]guanine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of N2-isobutyryl-9-[3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-β-D-arabinofuranosyl]guanine

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N2-isobutyryl-9-[3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-β-D-arabinofuranosyl]guanine

There total 1 articles about N2-isobutyryl-9-[3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-β-D-arabinofuranosyl]guanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 38819-10-2
9-β-D-arabinofuranosylguanine

: 160684-47-9
N2-isobutyryl-9-[3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-β-D-arabinofuranosyl]guanine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) TMSCl, pyridine, 3.) NH₄OH

2: pyridine

With pyridine; ammonium hydroxide; chloro-trimethyl-silane;
DOI:10.1080/07328319708006246

Reference yield:

: 160684-47-9
N2-isobutyryl-9-[3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-β-D-arabinofuranosyl]guanine

: 78842-13-4
2'-deoxy-2'-fluoroguanosine

Guidance literature:: Multi-step reaction with 8 steps

2: HF*pyridine

3: TsOH / dioxane

4: NaOH / pyridine; methanol

5: DMAP / CH₂Cl₂

6: TBAF / tetrahydrofuran

7: Dowex-50 / methanol

8: NH₄OH / 24 h / 55 °C

With dmap; ammonium hydroxide; sodium hydroxide; Dowex-50; tetrabutyl ammonium fluoride; toluene-4-sulfonic acid; pyridine hydrogenfluoride; In tetrahydrofuran; 1,4-dioxane; pyridine; methanol; dichloromethane;
DOI:10.1080/07328319708006246

Reference yield:

: 160684-47-9
N2-isobutyryl-9-[3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-β-D-arabinofuranosyl]guanine

: 80681-25-0
2’-fluoro-N2-isobutyryl-2’-deoxyguanosine

Guidance literature:: Multi-step reaction with 7 steps

2: HF*pyridine

3: TsOH / dioxane

4: NaOH / pyridine; methanol

5: DMAP / CH₂Cl₂

6: TBAF / tetrahydrofuran

7: Dowex-50 / methanol

With dmap; sodium hydroxide; Dowex-50; tetrabutyl ammonium fluoride; toluene-4-sulfonic acid; pyridine hydrogenfluoride; In tetrahydrofuran; 1,4-dioxane; pyridine; methanol; dichloromethane;
DOI:10.1080/07328319708006246