2-acetoxy-3-(benzyloxycarbonylamino)-6-(dibenzyloxycarbonylguanidino)hexanenitril

Base Information

Chemical Name:2-acetoxy-3-(benzyloxycarbonylamino)-6-(dibenzyloxycarbonylguanidino)hexanenitril
CAS No.:474081-05-5
Molecular Formula:C₃₃H₃₅N₅O₈
Molecular Weight:629.67
Hs Code.:

Synonyms:2-acetoxy-3-(benzyloxycarbonylamino)-6-(dibenzyloxycarbonylguanidino)hexanenitril

Suppliers and Price of 2-acetoxy-3-(benzyloxycarbonylamino)-6-(dibenzyloxycarbonylguanidino)hexanenitril

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-acetoxy-3-(benzyloxycarbonylamino)-6-(dibenzyloxycarbonylguanidino)hexanenitril

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-acetoxy-3-(benzyloxycarbonylamino)-6-(dibenzyloxycarbonylguanidino)hexanenitril

There total 3 articles about 2-acetoxy-3-(benzyloxycarbonylamino)-6-(dibenzyloxycarbonylguanidino)hexanenitril which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 143-33-9,25596-52-5
sodium cyanide

: 108-24-7
acetic anhydride

: 139033-47-9
Z-Arg-(Z₂)-H

: 474081-05-5
2-acetoxy-3-(benzyloxycarbonylamino)-6-(dibenzyloxycarbonylguanidino)hexanenitril

Guidance literature:: With N-benzyl-N,N,N-triethylammonium chloride; In dichloromethane; at 0 - 5 ℃; for 0.5h;
DOI:10.1021/jm011110z

Reference yield:

: 14611-34-8
N^α,N^δ,N^ω-tris(benzyloxycarbonyl)-L-arginine

: 474081-05-5
2-acetoxy-3-(benzyloxycarbonylamino)-6-(dibenzyloxycarbonylguanidino)hexanenitril

Guidance literature:: Multi-step reaction with 3 steps

1: 88.8 percent / TBTU; Et₃N / CH₂Cl₂ / 1 h / 20 °C / pH 8

2: diisobutylaluminumhydride / CH₂Cl₂ / 1 h / -78 °C

3: 17 g / aq. triethylbenzylammonium chloride / CH₂Cl₂ / 0.5 h / 0 - 5 °C

With N-benzyl-N,N,N-triethylammonium chloride; diisobutylaluminium hydride; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine; In dichloromethane;
DOI:10.1021/jm011110z

Reference yield:

: 185744-58-5
N^α,N^δ,N-tri-benzyloxycarbonyl-L-arginine methyl ester

: 474081-05-5
2-acetoxy-3-(benzyloxycarbonylamino)-6-(dibenzyloxycarbonylguanidino)hexanenitril

Guidance literature:: Multi-step reaction with 2 steps

1: diisobutylaluminumhydride / CH₂Cl₂ / 1 h / -78 °C

2: 17 g / aq. triethylbenzylammonium chloride / CH₂Cl₂ / 0.5 h / 0 - 5 °C

With N-benzyl-N,N,N-triethylammonium chloride; diisobutylaluminium hydride; In dichloromethane;
DOI:10.1021/jm011110z