3-<<<3-(1,1-dimethylethyl)-1-methyl-1H-pyrazol-5-yl>carbonyl>amino>-5-methoxybenzoic acid

Base Information

• Chemical Name: 3-<<<3-(1,1-dimethylethyl)-1-methyl-1H-pyrazol-5-yl>carbonyl>amino>-5-methoxybenzoic acid
• CAS No.: 220965-93-5
• Molecular Formula: C₁₇H₂₁N₃O₄
• Molecular Weight: 331.371
• Mol file: 220965-93-5.mol

Synonyms:3-<<<3-(1,1-dimethylethyl)-1-methyl-1H-pyrazol-5-yl>carbonyl>amino>-5-methoxybenzoic acid

Chemical Property of 3-<<<3-(1,1-dimethylethyl)-1-methyl-1H-pyrazol-5-yl>carbonyl>amino>-5-methoxybenzoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-<<<3-(1,1-dimethylethyl)-1-methyl-1H-pyrazol-5-yl>carbonyl>amino>-5-methoxybenzoic acid

There total 3 articles about 3-<<<3-(1,1-dimethylethyl)-1-methyl-1H-pyrazol-5-yl>carbonyl>amino>-5-methoxybenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

3-<<<3-(1,1-dimethylethyl)-1-methyl-1H-pyrazol-5-yl>carbonyl>amino>-5-methoxybenzoic acid, methyl ester (220965-92-4) → 3-<<<3-(1,1-dimethylethyl)-1-methyl-1H-pyrazol-5-yl>carbonyl>amino>-5-methoxybenzoic acid (220965-93-5)

Guidance literature:

With potassium carbonate; In methanol; for 15h; Ambient temperature;

DOI:10.1002/jhet.5570350646

Reference yield:

3-tert-Butyl-1-methyl-1H-pyrazole-5-carbonyl chloride (160842-62-6) → 3-<<<3-(1,1-dimethylethyl)-1-methyl-1H-pyrazol-5-yl>carbonyl>amino>-5-methoxybenzoic acid (220965-93-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 61 percent / pyridine / CH₂Cl₂ / 17 h / Ambient temperature

2: 88 percent / aq. K₂CO₃ / methanol / 15 h / Ambient temperature

With pyridine; potassium carbonate; In methanol; dichloromethane;

DOI:10.1002/jhet.5570350646

Reference yield:

methyl 3-amino-5-methoxybenzoate (217314-47-1) → 3-<<<3-(1,1-dimethylethyl)-1-methyl-1H-pyrazol-5-yl>carbonyl>amino>-5-methoxybenzoic acid (220965-93-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 61 percent / pyridine / CH₂Cl₂ / 17 h / Ambient temperature

2: 88 percent / aq. K₂CO₃ / methanol / 15 h / Ambient temperature

With pyridine; potassium carbonate; In methanol; dichloromethane;

DOI:10.1002/jhet.5570350646

upstream raw materials:

3-<<<3-(1,1-dimethylethyl)-1-methyl-1H-pyrazol-5-yl>carbonyl>amino>-5-methoxybenzoic acid, methyl ester

3-tert-Butyl-1-methyl-1H-pyrazole-5-carbonyl chloride

methyl 3-amino-5-methoxybenzoate