(3R)-7-((1H-benzo[d][1,2,3]triazol-1-yl)methyl)-8-cyclopropyl-5-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyridine-3-carboxylate lithium salt

Base Information

• Chemical Name: (3R)-7-((1H-benzo[d][1,2,3]triazol-1-yl)methyl)-8-cyclopropyl-5-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyridine-3-carboxylate lithium salt
• CAS No.: 1374967-39-1
• Molecular Formula: C₁₈H₁₅N₄O₃S*Li
• Molecular Weight: 374.349
• Mol file: 1374967-39-1.mol

Synonyms:(3R)-7-((1H-benzo[d][1,2,3]triazol-1-yl)methyl)-8-cyclopropyl-5-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyridine-3-carboxylate lithium salt

Chemical Property of (3R)-7-((1H-benzo[d][1,2,3]triazol-1-yl)methyl)-8-cyclopropyl-5-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyridine-3-carboxylate lithium salt

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3R)-7-((1H-benzo[d][1,2,3]triazol-1-yl)methyl)-8-cyclopropyl-5-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyridine-3-carboxylate lithium salt

There total 1 articles about (3R)-7-((1H-benzo[d][1,2,3]triazol-1-yl)methyl)-8-cyclopropyl-5-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyridine-3-carboxylate lithium salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(1H-1,2,3-benzotriazol-1-yl)acetic acid (4144-64-3) → (3R)-7-((1H-benzo[d][1,2,3]triazol-1-yl)methyl)-8-cyclopropyl-5-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyridine-3-carboxylate lithium salt (1374967-39-1)

Guidance literature:

Multi-step reaction with 3 steps

1.1: dmap; dicyclohexyl-carbodiimide / dichloromethane / 20 °C / Inert atmosphere

2.1: trifluoroacetic acid / 1,2-dichloro-ethane / Inert atmosphere

2.2: 0.03 h / 140 °C / Microwave irradiation; Inert atmosphere

3.1: lithium hydroxide / tetrahydrofuran; water / 20 °C

With dmap; dicyclohexyl-carbodiimide; trifluoroacetic acid; lithium hydroxide; In tetrahydrofuran; dichloromethane; water; 1,2-dichloro-ethane;

DOI:10.1016/j.bmc.2012.01.048

upstream raw materials:

2-(1H-1,2,3-benzotriazol-1-yl)acetic acid