2,2,3,3-TETRAFLUORO-1,4-BENZODIOXENE-6-CARBALDEHYDE

Base Information

• Chemical Name: 2,2,3,3-TETRAFLUORO-1,4-BENZODIOXENE-6-CARBALDEHYDE
• CAS No.: 159276-63-8
• Molecular Formula: C₉H₄F₄O₃
• Molecular Weight: 236.123
• Hs Code.: 2932990090
• Mol file: 159276-63-8.mol

Synonyms:6-Formyl-2,2,3,3-tetrafluoro-1,4-benzodioxane

Chemical Property of 2,2,3,3-TETRAFLUORO-1,4-BENZODIOXENE-6-CARBALDEHYDE

Chemical Property:

• PSA: 35.53000
• LogP: 2.45590

Purity/Quality:

2,2,3,3-Tetrafluoro-1,4-benzodioxene-6-carbaldehyde 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R36/37/38:
• Hazard Codes: R36/37/38:
• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,2,3,3-TETRAFLUORO-1,4-BENZODIOXENE-6-CARBALDEHYDE

There total 1 articles about 2,2,3,3-TETRAFLUORO-1,4-BENZODIOXENE-6-CARBALDEHYDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 12.7%

→ 3-(1,1,2,2-tetrafluoroethoxy)-4-hydroxybenzaldehyde (220004-39-7) + 2,2,3,3-tetrafluorobenzo-1,4-dioxin-6-carbaldehyde (159276-63-8)

Guidance literature:

Reference yield:

2,2,3,3-tetrafluorobenzo-1,4-dioxin-6-carbaldehyde (159276-63-8) → 1,1,1-trifluoro-3-[(3-phenoxy-phenyl)-(2,2,3,3-tetrafluoro-2,3-dihydro-benzo[1,4]dioxin-6-ylmethyl)-amino]-propan-2-ol

Guidance literature:

Multi-step reaction with 2 steps

1: Yb(CF₃SO₃)3 / acetonitrile / 50 °C

With ytterbium(III) triflate; In acetonitrile;

DOI:10.1021/jm020038h

Reference yield:

3-phenoxyaniline (3586-12-7) + 2,2,3,3-tetrafluorobenzo-1,4-dioxin-6-carbaldehyde (159276-63-8) → (3-phenoxy-phenyl)-(2,2,3,3-tetrafluoro-2,3-dihydro-benzo[1,4]dioxin-6-ylmethyl)-amine

Guidance literature:

DOI:10.1021/jm020038h

Refernces