1H-imidazo[1,2-b]pyrazole-6-carboxylic acid

Base Information

Chemical Name:1H-imidazo[1,2-b]pyrazole-6-carboxylic acid
CAS No.:159181-78-9
Molecular Formula:C₆H₅N₃O₂
Molecular Weight:151.125
Hs Code.:
DSSTox Substance ID:DTXSID90434057
Wikidata:Q82248367
Mol file:159181-78-9.mol

Synonyms:1H-imidazo[1,2-b]pyrazole-6-carboxylic acid;159181-78-9;5H-imidazo[1,2-b]pyrazole-6-carboxylic acid;1H-PYRAZOLO[1,5-A]IMIDAZOLE-6-CARBOXYLIC ACID;1H-Imidazo[1,2-b]pyrazole-6-carboxylicacid(9CI);1H-Imidazo[1,2-b]pyrazole-6-carboxylicacid;SCHEMBL1898513;SCHEMBL2267926;DTXSID90434057;AKOS022175993;AB55663;CS-0447487;EN300-88114;J-504664;F8887-5188

Suppliers and Price of 1H-imidazo[1,2-b]pyrazole-6-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1H-Imidazo[1,2-b]pyrazole-6-carboxylicacid 95+%
1g
$ 1307.00

American Custom Chemicals Corporation
1H-IMIDAZO[1,2-B]PYRAZOLE-6-CARBOXYLIC ACID 95.00%
5G
$ 6491.91

American Custom Chemicals Corporation
1H-IMIDAZO[1,2-B]PYRAZOLE-6-CARBOXYLIC ACID 95.00%
2.5G
$ 5067.04

American Custom Chemicals Corporation
1H-IMIDAZO[1,2-B]PYRAZOLE-6-CARBOXYLIC ACID 95.00%
1G
$ 3799.53

Alichem
1H-Imidazo[1,2-b]pyrazole-6-carboxylicacid
1g
$ 1068.58

Total 5 raw suppliers

Chemical Property of 1H-imidazo[1,2-b]pyrazole-6-carboxylic acid

Chemical Property:

Refractive Index:1.793
PSA：70.39000
Density:1.741g/cm³
LogP:0.36060
XLogP3:0.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:151.038176411
Heavy Atom Count:11
Complexity:185

Purity/Quality:

97% ^*data from raw suppliers

1H-Imidazo[1,2-b]pyrazole-6-carboxylicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CN2C(=N1)C=C(N2)C(=O)O

Technology Process of 1H-imidazo[1,2-b]pyrazole-6-carboxylic acid

There total 3 articles about 1H-imidazo[1,2-b]pyrazole-6-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.5%

: 159181-77-8
ethyl imidazo<1,2-b>pyrazole-6-carboxylate

: 159181-78-9
6-carboxy-1H-imidazo<1,2-b>pyrazole

Guidance literature:: With sodium hydroxide; for 1h; Ambient temperature;
DOI:10.1002/jhet.5570310408

Reference yield:

: 222056-28-2
ethyl 1-(2,2-diethoxyethyl)-5-aminopyrazole-3-carboxylate

: 159181-78-9
6-carboxy-1H-imidazo<1,2-b>pyrazole

Guidance literature:: Multi-step reaction with 2 steps

1: 43.5 percent / HCl*Et₂O / tetrahydrofuran / 2 h / Ambient temperature

2: 58.5 percent / 4N NaOH / 1 h / Ambient temperature

With sodium hydroxide; hydrochloric acid diethyl ether; In tetrahydrofuran;
DOI:10.1080/00397919908085772