7-pentofuranosyl-7H-tetrazolo[5,1-i]purine

Base Information

• Chemical Name: 7-pentofuranosyl-7H-tetrazolo[5,1-i]purine
• CAS No.: 37082-52-3
• Molecular Formula: C₁₀H₁₁N₇O₄
• Molecular Weight: 293.242
• Mol file: 37082-52-3.mol

Synonyms:(1R)-1-tetrazolo[5,1-i]purin-7-yl-D-1,4-anhydro-ribitol

Chemical Property of 7-pentofuranosyl-7H-tetrazolo[5,1-i]purine

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 7-pentofuranosyl-7H-tetrazolo[5,1-i]purine

There total 4 articles about 7-pentofuranosyl-7H-tetrazolo[5,1-i]purine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

O6-(benzotriazol-1-yl)inosine (927818-53-9) → (1R)-1-tetrazolo[5,1-i]purin-7-yl-D-1,4-anhydro-ribitol (37082-52-3)

Guidance literature:

With polymer-supported azide; In N,N-dimethyl-formamide; at 50 ℃; for 5h; Inert atmosphere;

DOI:10.1021/jo902342z

Reference yield:

→ (1R)-1-tetrazolo[5,1-i]purin-7-yl-D-1,4-anhydro-ribitol (37082-52-3)

Guidance literature:

With acetic acid; sodium nitrite;

DOI:10.1021/ja01536a044

Reference yield:

→ (1R)-1-tetrazolo[5,1-i]purin-7-yl-D-1,4-anhydro-ribitol (37082-52-3)

Guidance literature:

With methanol; sodium azide;

DOI:10.1021/jo00893a027

upstream raw materials:

6-Chloropurine riboside

O⁶-(benzotriazol-1-yl)inosine

Downstream raw materials:

1-(β-D-ribofuranosyl)-4,6-dihydroimidazo[4,5-f][1,3,5]triazepin-5(1H)-one

adenosine