(R,S)-2-N-Boc-3-Phenylpropyl cyanide

Base Information

Chemical Name:(R,S)-2-N-Boc-3-Phenylpropyl cyanide
CAS No.:159025-89-5
Molecular Formula:C15H20 N2 O2
Molecular Weight:260.336
Hs Code.:
Mol file:159025-89-5.mol

Synonyms:(R,S)-2-N-Boc-3-Phenylpropyl cyanide

Suppliers and Price of (R,S)-2-N-Boc-3-Phenylpropyl cyanide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (R,S)-2-N-Boc-3-Phenylpropyl cyanide

Chemical Property:

PSA：62.12000
LogP:3.42698

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (R,S)-2-N-Boc-3-Phenylpropyl cyanide

There total 1 articles about (R,S)-2-N-Boc-3-Phenylpropyl cyanide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 877374-06-6
Toluene-4-sulfonic acid-2-tert-butoxycarbonylamino-3-phenylpropyl ester

: 143-33-9,25596-52-5
sodium cyanide

: 159025-89-5
3-[(t-butoxycarbonyl)amino]-4-phenylbutanenitrile

Guidance literature:: In DMF (N,N-dimethyl-formamide); at 20 ℃; for 48h;

Reference yield:

: 159025-89-5
3-[(t-butoxycarbonyl)amino]-4-phenylbutanenitrile

: 15099-85-1
3(S)-amino-4-phenylbutyric acid

Guidance literature:: With hydrogenchloride; water; Heating / reflux;

Reference yield:

: 159025-89-5
3-[(t-butoxycarbonyl)amino]-4-phenylbutanenitrile

: 2-benzyl-6-methyl-2,3-dihydro-1H-pyridin-4-one

Guidance literature:: Multi-step reaction with 5 steps

1.1: HCl / dioxane / 12 h / Heating

2.1: aq. NaHCO₃ / CH₂Cl₂

2.2: methanol / 0.5 h / 20 °C

3.1: 81 percent / AcOH / benzene / Heating

4.1: 84 percent / tBuOK / 2-methyl-propan-2-ol / 4 h / 50 °C

5.1: 92 percent / TFA / CH₂Cl₂ / 4 h / 50 °C

With hydrogenchloride; potassium tert-butylate; sodium hydrogencarbonate; acetic acid; trifluoroacetic acid; In 1,4-dioxane; dichloromethane; tert-butyl alcohol; benzene;
DOI:10.1055/s-2002-33648