N-(hex-5-en-1-yl)-N-[(3S)-1-(hex-5-en-1-yl)-2-oxoazetidin-3-yl]-2-phenoxyacetamide

Base Information

Chemical Name:N-(hex-5-en-1-yl)-N-[(3S)-1-(hex-5-en-1-yl)-2-oxoazetidin-3-yl]-2-phenoxyacetamide
CAS No.:1359659-12-3
Molecular Formula:C₂₃H₃₂N₂O₃
Molecular Weight:384.519
Hs Code.:

Synonyms:N-(hex-5-en-1-yl)-N-[(3S)-1-(hex-5-en-1-yl)-2-oxoazetidin-3-yl]-2-phenoxyacetamide

Suppliers and Price of N-(hex-5-en-1-yl)-N-[(3S)-1-(hex-5-en-1-yl)-2-oxoazetidin-3-yl]-2-phenoxyacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(hex-5-en-1-yl)-N-[(3S)-1-(hex-5-en-1-yl)-2-oxoazetidin-3-yl]-2-phenoxyacetamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(hex-5-en-1-yl)-N-[(3S)-1-(hex-5-en-1-yl)-2-oxoazetidin-3-yl]-2-phenoxyacetamide

There total 5 articles about N-(hex-5-en-1-yl)-N-[(3S)-1-(hex-5-en-1-yl)-2-oxoazetidin-3-yl]-2-phenoxyacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

: N-[(3S)-2-oxoazetidin-3-yl]-2-phenoxyacetamide

: 2695-47-8
6-Bromo-1-hexene

: 1359659-12-3
N-(hex-5-en-1-yl)-N-[(3S)-1-(hex-5-en-1-yl)-2-oxoazetidin-3-yl]-2-phenoxyacetamide

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 - 20 ℃; for 12h; Inert atmosphere;
DOI:10.1002/asia.201100732

Reference yield:

: 1104761-72-9
(2S)-3-hydroxy-2-(2-phenoxyacetamido)propanoic acid

: 1359659-12-3
N-(hex-5-en-1-yl)-N-[(3S)-1-(hex-5-en-1-yl)-2-oxoazetidin-3-yl]-2-phenoxyacetamide

Guidance literature:: Multi-step reaction with 4 steps

1: dicyclohexyl-carbodiimide / tetrahydrofuran / 12 h / 0 - 20 °C / Inert atmosphere

2: triethylamine; triphenylphosphine / tetrachloromethane; acetonitrile / 12 h / 0 - 20 °C / Inert atmosphere

3: hydrogen / methanol; water; ethyl acetate / 12 h / 20 °C / 760.05 Torr

4: sodium hydride / N,N-dimethyl-formamide; mineral oil / 12 h / 0 - 20 °C / Inert atmosphere

With hydrogen; sodium hydride; triethylamine; dicyclohexyl-carbodiimide; triphenylphosphine; In tetrahydrofuran; methanol; tetrachloromethane; water; ethyl acetate; N,N-dimethyl-formamide; acetonitrile; mineral oil;
DOI:10.1002/asia.201100732

Reference yield:

: 1359659-07-6
(2S)-N-(benzyloxy)-3-hydroxy-2-(2-phenoxyacetamido)propanamide

: 1359659-12-3
N-(hex-5-en-1-yl)-N-[(3S)-1-(hex-5-en-1-yl)-2-oxoazetidin-3-yl]-2-phenoxyacetamide

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine; triphenylphosphine / tetrachloromethane; acetonitrile / 12 h / 0 - 20 °C / Inert atmosphere

2: hydrogen / methanol; water; ethyl acetate / 12 h / 20 °C / 760.05 Torr

3: sodium hydride / N,N-dimethyl-formamide; mineral oil / 12 h / 0 - 20 °C / Inert atmosphere

With hydrogen; sodium hydride; triethylamine; triphenylphosphine; In methanol; tetrachloromethane; water; ethyl acetate; N,N-dimethyl-formamide; acetonitrile; mineral oil;
DOI:10.1002/asia.201100732