(2-{3-oxo-3-[4-(5-p-tolyl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonylamino]-propyl}-phenyl)-carbamic acid tert-butyl ester

Base Information

• Chemical Name: (2-{3-oxo-3-[4-(5-p-tolyl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonylamino]-propyl}-phenyl)-carbamic acid tert-butyl ester
• CAS No.: 1233497-38-5
• Molecular Formula: C₃₁H₃₁F₃N₄O₅S
• Molecular Weight: 628.672
• Mol file: 1233497-38-5.mol

Synonyms:(2-{3-oxo-3-[4-(5-p-tolyl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonylamino]-propyl}-phenyl)-carbamic acid tert-butyl ester

Chemical Property of (2-{3-oxo-3-[4-(5-p-tolyl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonylamino]-propyl}-phenyl)-carbamic acid tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2-{3-oxo-3-[4-(5-p-tolyl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonylamino]-propyl}-phenyl)-carbamic acid tert-butyl ester

There total 1 articles about (2-{3-oxo-3-[4-(5-p-tolyl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonylamino]-propyl}-phenyl)-carbamic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

C14H19NO4 (1070955-54-2) + 4-[5-(4-(methyl)phenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulphonamide (169590-42-5,194044-54-7) → (2-{3-oxo-3-[4-(5-p-tolyl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonylamino]-propyl}-phenyl)-carbamic acid tert-butyl ester (1233497-38-5)

Guidance literature:

C₁₄H₁₉NO₄; 4-[5-(4-(methyl)phenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulphonamide; With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In 1,2-dichloro-ethane; tert-butyl alcohol;

In ethyl acetate; 1,2-dichloro-ethane; tert-butyl alcohol; for 2h;

Reference yield:

(2-{3-oxo-3-[4-(5-p-tolyl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonylamino]-propyl}-phenyl)-carbamic acid tert-butyl ester (1233497-38-5) → C26H23F3N4O3S (1233497-39-6)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 0 ℃;

DOI:10.1016/j.bmcl.2011.09.071

upstream raw materials:

C₁₄H₁₉NO₄

4-[5-(4-(methyl)phenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulphonamide

Downstream raw materials:

C₂₆H₂₃F₃N₄O₃S