ethyl 4-(4-N-acetylamino)phenoxybutyrate

Base Information

• Chemical Name: ethyl 4-(4-N-acetylamino)phenoxybutyrate
• CAS No.: 1000774-76-4
• Molecular Formula: C₁₄H₁₉NO₄
• Molecular Weight: 265.309
• Mol file: 1000774-76-4.mol

Synonyms:ethyl 4-(4-N-acetylamino)phenoxybutyrate

Chemical Property of ethyl 4-(4-N-acetylamino)phenoxybutyrate

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of ethyl 4-(4-N-acetylamino)phenoxybutyrate

There total 1 articles about ethyl 4-(4-N-acetylamino)phenoxybutyrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

Ethyl 4-bromobutyrate (2969-81-5) + 4-acetaminophenol (103-90-2,8055-08-1) → ethyl 4-(4-N-acetylamino)phenoxybutyrate (1000774-76-4)

Guidance literature:

With potassium carbonate; at 70 ℃; for 16h;

DOI:10.1080/00397911.2015.1041048

Reference yield: 71.0%

ethyl 4-(4-N-acetylamino)phenoxybutyrate (1000774-76-4) → 4-(4-aminophenoxy)butyric acid hydrochloride

Guidance literature:

With hydrogenchloride; In water; for 2h; Reflux;

DOI:10.1080/00397911.2015.1041048

Reference yield:

ethyl 4-(4-N-acetylamino)phenoxybutyrate (1000774-76-4) → 4-(4-acetamidophenyl)butyric acid (937600-99-2)

Guidance literature:

With sodium hydroxide; In methanol; at 20 ℃; for 7h;

DOI:10.1021/jm000169n

upstream raw materials:

Ethyl 4-bromobutyrate

4-acetaminophenol

Downstream raw materials:

4-(4-acetamidophenyl)butyric acid

4-(4-aminophenoxy)butyric acid