(2S,3S,4R)-2-[(E)-1,5-dimethylhex-1-enyl]-3-methoxy-4-p-methoxybenzyloxy-6-methylenecyclohexanone

Base Information

• Chemical Name: (2S,3S,4R)-2-[(E)-1,5-dimethylhex-1-enyl]-3-methoxy-4-p-methoxybenzyloxy-6-methylenecyclohexanone
• CAS No.: 527755-53-9
• Molecular Formula: C₂₄H₃₄O₄
• Molecular Weight: 386.532
• Mol file: 527755-53-9.mol

Synonyms:(2S,3S,4R)-2-[(E)-1,5-dimethylhex-1-enyl]-3-methoxy-4-p-methoxybenzyloxy-6-methylenecyclohexanone

Chemical Property of (2S,3S,4R)-2-[(E)-1,5-dimethylhex-1-enyl]-3-methoxy-4-p-methoxybenzyloxy-6-methylenecyclohexanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2S,3S,4R)-2-[(E)-1,5-dimethylhex-1-enyl]-3-methoxy-4-p-methoxybenzyloxy-6-methylenecyclohexanone

There total 2 articles about (2S,3S,4R)-2-[(E)-1,5-dimethylhex-1-enyl]-3-methoxy-4-p-methoxybenzyloxy-6-methylenecyclohexanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

→ (2S,3S,4R)-2-[(E)-1,5-dimethylhex-1-enyl]-3-methoxy-4-p-methoxybenzyloxy-6-methylenecyclohexanone (527755-53-9)

Guidance literature:

Reference yield:

1-[(1R,5S,6S)-3-(tert-Butyl-dimethyl-silanyloxymethyl)-5-((E)-1,5-dimethyl-hex-1-enyl)-6-methoxy-4-triethylsilanyloxy-cyclohex-3-enyloxymethyl]-4-methoxy-benzene → (2S,3S,4R)-2-[(E)-1,5-dimethylhex-1-enyl]-3-methoxy-4-p-methoxybenzyloxy-6-methylenecyclohexanone (527755-53-9)

Guidance literature:

With trifluoroacetic acid; In tetrahydrofuran; water; at 20 ℃; for 1.5h;

DOI:10.1021/jo035065+

Reference yield: 36.0%

(2S,3S,4R)-2-[(E)-1,5-dimethylhex-1-enyl]-3-methoxy-4-p-methoxybenzyloxy-6-methylenecyclohexanone (527755-53-9) → (2S,3S,4R,6R)-2-[(E)-1,5-dimethylhex-1-enyl]-3-methoxy-4-p-methoxybenzyloxy-6-methylcyclohexanone (527755-55-1) + (2S,3S,4R,6S)-2-[(E)-1,5-dimethylhex-1-enyl]-3-methoxy-4-p-methoxybenzyloxy-6-methylcyclohexanone

Guidance literature:

nickel; In tetrahydrofuran; water; at 0 ℃; for 2h;

DOI:10.1021/jo035065+

Downstream raw materials:

(2S,3S,4R,6R)-2-[(E)-1,5-dimethylhex-1-enyl]-3-methoxy-4-p-methoxybenzyloxy-6-methylcyclohexanone

(3R,4S,5S,6R,8R)-4-[(E)-1,5-dimethylhex-1-enyl]-5-methoxy-6-p-methoxybenzyloxy-8-methyl-1-oxaspiro[2.5]octane