(2S,4S,5R)-2-[(R)-hydroxy(6-methoxyquinolin-4-yl)methyl]-2-methyl-5-vinylquinuclidinium bis-(2-phenylethyl)dithiophosphinate

Base Information

• Chemical Name: (2S,4S,5R)-2-[(R)-hydroxy(6-methoxyquinolin-4-yl)methyl]-2-methyl-5-vinylquinuclidinium bis-(2-phenylethyl)dithiophosphinate
• CAS No.: 1391013-63-0
• Molecular Formula: C₁₆H₁₉PS₂*C₂₀H₂₄N₂O₂
• Molecular Weight: 630.855
• Mol file: 1391013-63-0.mol

Synonyms:(2S,4S,5R)-2-[(R)-hydroxy(6-methoxyquinolin-4-yl)methyl]-2-methyl-5-vinylquinuclidinium bis-(2-phenylethyl)dithiophosphinate

Chemical Property of (2S,4S,5R)-2-[(R)-hydroxy(6-methoxyquinolin-4-yl)methyl]-2-methyl-5-vinylquinuclidinium bis-(2-phenylethyl)dithiophosphinate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2S,4S,5R)-2-[(R)-hydroxy(6-methoxyquinolin-4-yl)methyl]-2-methyl-5-vinylquinuclidinium bis-(2-phenylethyl)dithiophosphinate

There total 2 articles about (2S,4S,5R)-2-[(R)-hydroxy(6-methoxyquinolin-4-yl)methyl]-2-methyl-5-vinylquinuclidinium bis-(2-phenylethyl)dithiophosphinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

bis(2-phenethyl)phosphine (93017-30-2) + quinine (130-95-0) → (2S,4S,5R)-2-[(R)-hydroxy(6-methoxyquinolin-4-yl)methyl]-2-methyl-5-vinylquinuclidinium bis-(2-phenylethyl)dithiophosphinate (1391013-63-0)

Guidance literature:

With sulfur; In ethanol; at 23 - 60 ℃; for 0.333333h; Inert atmosphere;

DOI:10.1007/s10593-012-1013-3

Reference yield:

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) → (2S,4S,5R)-2-[(R)-hydroxy(6-methoxyquinolin-4-yl)methyl]-2-methyl-5-vinylquinuclidinium bis-(2-phenylethyl)dithiophosphinate (1391013-63-0)

Guidance literature:

Multi-step reaction with 2 steps

1: phosphorus / Inert atmosphere

2: sulfur / ethanol / 0.33 h / 23 - 60 °C / Inert atmosphere

With phosphorus; sulfur; In ethanol;

DOI:10.1007/s10593-012-1013-3

upstream raw materials:

bis(2-phenethyl)phosphine

quinine

styrene