5-((4-broMo-2-fluorophenyl)aMino)-4-fluoro-1-Methyl-1H-benzo[d]iMidazole-6-carboxylic acid

Base Information

Chemical Name:5-((4-broMo-2-fluorophenyl)aMino)-4-fluoro-1-Methyl-1H-benzo[d]iMidazole-6-carboxylic acid
CAS No.:1415564-99-6
Molecular Formula:C₁₅H₁₀BrF₂N₃O₂
Molecular Weight:382.164
Hs Code.:
Mol file:1415564-99-6.mol

Synonyms:6-(4-bromo-2-fluorophenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid

Suppliers and Price of 5-((4-broMo-2-fluorophenyl)aMino)-4-fluoro-1-Methyl-1H-benzo[d]iMidazole-6-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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ChemScene
5-((4-bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxylicacid
1g
$ 700.00

Total 10 raw suppliers

Chemical Property of 5-((4-broMo-2-fluorophenyl)aMino)-4-fluoro-1-Methyl-1H-benzo[d]iMidazole-6-carboxylic acid

Chemical Property:

Purity/Quality:

99%, ^*data from raw suppliers

5-((4-bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxylicacid ^*data from reagent suppliers

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Pictogram(s):
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MSDS Files:

Useful:

Technology Process of 5-((4-broMo-2-fluorophenyl)aMino)-4-fluoro-1-Methyl-1H-benzo[d]iMidazole-6-carboxylic acid

There total 9 articles about 5-((4-broMo-2-fluorophenyl)aMino)-4-fluoro-1-Methyl-1H-benzo[d]iMidazole-6-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1415559-93-1
methyl 5-[(4-bromo-2-fluorophenyl)amino]-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxylate

: 1415564-99-6
6-(4-bromo-2-fluorophenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid

Guidance literature:: With water; sodium hydroxide; In tetrahydrofuran; for 2h;

Reference yield:

: 6-(4-bromo-2-fluorophenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid ethyl ester

: 1415564-99-6
6-(4-bromo-2-fluorophenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid

Guidance literature:: With water; sodium hydroxide; In tetrahydrofuran; at 20 ℃;

Reference yield:

: 918321-20-7
methyl 5-amino-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxylate

: 1415564-99-6
6-(4-bromo-2-fluorophenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: caesium carbonate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene / toluene; 1,4-dioxane / 8 h / 99 °C / Inert atmosphere

2: sodium hydroxide; water / N,N-dimethyl-formamide / 3 h / 30 °C / Inert atmosphere

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; water; caesium carbonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; sodium hydroxide; In 1,4-dioxane; N,N-dimethyl-formamide; toluene;