(R)-1,1-dimethyl-2-[2-((indan-2-yl)(2-methylphenyl)amino)ethyl]piperidinium bromide

Base Information

Chemical Name:(R)-1,1-dimethyl-2-[2-((indan-2-yl)(2-methylphenyl)amino)ethyl]piperidinium bromide
CAS No.:1393836-45-7
Molecular Formula:Br*C₂₅H₃₅N₂
Molecular Weight:443.47
Hs Code.:

Synonyms:(R)-1,1-dimethyl-2-[2-((indan-2-yl)(2-methylphenyl)amino)ethyl]piperidinium bromide

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Chemical Property of (R)-1,1-dimethyl-2-[2-((indan-2-yl)(2-methylphenyl)amino)ethyl]piperidinium bromide

Chemical Property:

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Technology Process of (R)-1,1-dimethyl-2-[2-((indan-2-yl)(2-methylphenyl)amino)ethyl]piperidinium bromide

There total 7 articles about (R)-1,1-dimethyl-2-[2-((indan-2-yl)(2-methylphenyl)amino)ethyl]piperidinium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 74-83-9
methyl bromide

: 1393837-05-2
C₂₄H₃₂N₂

: 1393836-45-7
(R)-1,1-dimethyl-2-[2-((indan-2-yl)(2-methylphenyl)amino)ethyl]piperidinium bromide

Guidance literature:: In tert-butyl methyl ether; at 20 ℃; for 20h;

Reference yield:

: 639458-46-1
(R)-2-(2-oxo-ethyl)-piperidine-1-carboxylic acid tert-butyl ester

: 1393836-45-7
(R)-1,1-dimethyl-2-[2-((indan-2-yl)(2-methylphenyl)amino)ethyl]piperidinium bromide

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium tris(acetoxy)borohydride / dichloromethane / 1.67 h / 0 - 20 °C / molecular sieves

2.1: lithium aluminium tetrahydride / tetrahydrofuran / 15.08 h / Reflux

2.2: 0 °C

3.1: tert-butyl methyl ether / 20 h / 20 °C

With lithium aluminium tetrahydride; sodium tris(acetoxy)borohydride; In tetrahydrofuran; dichloromethane; tert-butyl methyl ether;

Reference yield:

: 33237-88-6
Indan-2-yl-o-tolyl-amine

: 1393836-45-7
(R)-1,1-dimethyl-2-[2-((indan-2-yl)(2-methylphenyl)amino)ethyl]piperidinium bromide

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium tris(acetoxy)borohydride / dichloromethane / 1.67 h / 0 - 20 °C / molecular sieves

2.1: lithium aluminium tetrahydride / tetrahydrofuran / 15.08 h / Reflux

2.2: 0 °C

3.1: tert-butyl methyl ether / 20 h / 20 °C

With lithium aluminium tetrahydride; sodium tris(acetoxy)borohydride; In tetrahydrofuran; dichloromethane; tert-butyl methyl ether;