3-O-(2-bromomethyl)benzyl-1,2-O-isopropylidene-β-D-fructopyranose

Base Information

• Chemical Name: 3-O-(2-bromomethyl)benzyl-1,2-O-isopropylidene-β-D-fructopyranose
• CAS No.: 848347-56-8
• Molecular Formula: C₁₇H₂₃BrO₆
• Molecular Weight: 403.27
• Mol file: 848347-56-8.mol

Synonyms:3-O-(2-bromomethyl)benzyl-1,2-O-isopropylidene-β-D-fructopyranose

Chemical Property of 3-O-(2-bromomethyl)benzyl-1,2-O-isopropylidene-β-D-fructopyranose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-O-(2-bromomethyl)benzyl-1,2-O-isopropylidene-β-D-fructopyranose

There total 3 articles about 3-O-(2-bromomethyl)benzyl-1,2-O-isopropylidene-β-D-fructopyranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

3-O-(2-bromomethyl)benzyl-1,2:4,5-di-O-isopropylidene-β-D-fructopyranose (848347-55-7) → 3-O-(2-bromomethyl)benzyl-1,2-O-isopropylidene-β-D-fructopyranose (848347-56-8)

Guidance literature:

With acetic acid; In water; at 45 ℃; for 2h;

DOI:10.1021/ol052668u

Reference yield:

1,2;4,5-di-O-isopropylidene-β-D-(-)-fructopyranose (25018-67-1) → 3-O-(2-bromomethyl)benzyl-1,2-O-isopropylidene-β-D-fructopyranose (848347-56-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: NaH / dimethylformamide / 0.33 h / 20 °C

1.2: 91 percent / dimethylformamide / 24 h / 20 °C

2.1: 87 percent / acetic acid / H₂O / 2 h / 45 °C

With sodium hydride; acetic acid; In water; N,N-dimethyl-formamide;

DOI:10.1021/ol052668u

Reference yield:

α,α'-dibromo-o-xylene (91-13-4) → 3-O-(2-bromomethyl)benzyl-1,2-O-isopropylidene-β-D-fructopyranose (848347-56-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: NaH / dimethylformamide / 0.33 h / 20 °C

1.2: 91 percent / dimethylformamide / 24 h / 20 °C

2.1: 87 percent / acetic acid / H₂O / 2 h / 45 °C

With sodium hydride; acetic acid; In water; N,N-dimethyl-formamide;

DOI:10.1021/ol052668u

upstream raw materials:

3-O-(2-bromomethyl)benzyl-1,2:4,5-di-O-isopropylidene-β-D-fructopyranose

1,2;4,5-di-O-isopropylidene-β-D-(-)-fructopyranose

α,α'-dibromo-o-xylene

Downstream raw materials:

2,5-anhydro-2,5-imino-D-glucitol

2,5-dideoxy-2,5-imino-D-mannitol