Fmoc-D-alanyl chloride

Base Information

Chemical Name:Fmoc-D-alanyl chloride
CAS No.:144073-15-4
Molecular Formula:C18H16 Cl N O3
Molecular Weight:329.78
Hs Code.:
DSSTox Substance ID:DTXSID50456371
Wikidata:Q82278798
Mol file:144073-15-4.mol

Synonyms:Fmoc-D-alanyl chloride;Fmoc-D-Ala-Cl;144073-15-4;9H-FLUOREN-9-YLMETHYL N-[(2R)-1-CHLORO-1-OXOPROPAN-2-YL]CARBAMATE;Carbamic acid, N-[(1R)-2-chloro-1-methyl-2-oxoethyl]-, 9H-fluoren-9-ylmethyl ester;SCHEMBL1343999;DTXSID50456371;AFMYCMGTXVCJCH-LLVKDONJSA-N;(9-fluorenyl methoxycarbonyl)-D-alanine-chloride;n-(9-fluorenylmethoxy-carbonyl)-d-alanyl chloride;J-007910;(R)-(9H-fluoren-9-yl)methyl (1-chloro-1-oxopropan-2-yl)carbamate;(R)-(9H-fluoren-9-yl)methyl 1-chloro-1-oxopropan-2-ylcarbamate;9H-Fluoren-9-ylmethyl [(2R)-1-chloro-1-oxo-2-propanyl]carbamate

Suppliers and Price of Fmoc-D-alanyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Fmoc-D-alanyl chloride
500mg
$ 333.00

Matrix Scientific
Fmoc-D-Ala-Cl 95+%
10g
$ 630.00

Matrix Scientific
Fmoc-D-Ala-Cl 95+%
5g
$ 404.00

Matrix Scientific
Fmoc-D-Ala-Cl 95+%
1g
$ 152.00

Crysdot
Fmoc-D-Ala-Cl 95+%
10g
$ 314.00

American Custom Chemicals Corporation
FMOC-D-ALA-CL 95.00%
1G
$ 624.00

American Custom Chemicals Corporation
FMOC-D-ALA-CL 95.00%
5MG
$ 502.90

AK Scientific
Fmoc-D-Ala-Cl
10g
$ 900.00

Total 6 raw suppliers

Chemical Property of Fmoc-D-alanyl chloride

Chemical Property:

PSA：55.40000
LogP:4.06990
XLogP3:4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:329.0818711
Heavy Atom Count:23
Complexity:434

Purity/Quality:

99% ^*data from raw suppliers

Fmoc-D-alanyl chloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(=O)Cl)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
Isomeric SMILES:C[C@H](C(=O)Cl)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

Technology Process of Fmoc-D-alanyl chloride

There total 2 articles about Fmoc-D-alanyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 35661-38-2,35661-39-3,79990-15-1,136132-75-7
N-(9-fluorenylmethoxycarbonyl)-D-alanine

: 144073-15-4
(9H-fluoren-9-yl)methyl (R)-(1-chloro-1-oxopropan-2-yl)carbamate

Guidance literature:: With thionyl chloride; In dichloromethane; for 2h;
DOI:10.1021/jacs.9b03732

Reference yield:

: 35661-39-3,136132-75-7
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine

: 144073-15-4
(9H-fluoren-9-yl)methyl (R)-(1-chloro-1-oxopropan-2-yl)carbamate

Guidance literature:: With oxalyl dichloride; In dichloromethane; N,N-dimethyl-formamide; at 20 ℃; for 1h;
DOI:10.1021/op0341869

Reference yield: 83.0%

: 1115978-13-6
C₃₁H₂₉NO₂S

: 144073-15-4
(9H-fluoren-9-yl)methyl (R)-(1-chloro-1-oxopropan-2-yl)carbamate

: 1115978-08-9
C₄₉H₄₄N₂O₅S

Guidance literature:: C₃₁H₂₉NO₂S; With sodium hydride; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;

(9H-fluoren-9-yl)methyl (R)-(1-chloro-1-oxopropan-2-yl)carbamate; In tetrahydrofuran; for 2h; Inert atmosphere;
DOI:10.1021/ol8028093