C₂₁H₁₃F₅N₄O₃

Base Information

Chemical Name:C₂₁H₁₃F₅N₄O₃
CAS No.:1276034-20-8
Molecular Formula:C₂₁H₁₃F₅N₄O₃
Molecular Weight:464.351
Hs Code.:

C<sub>21</sub>H<sub>13</sub>F<sub>5</sub>N<sub>4</sub>O<sub>3</sub>

Synonyms:C₂₁H₁₃F₅N₄O₃

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₂₁H₁₃F₅N₄O₃

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Technology Process of C₂₁H₁₃F₅N₄O₃

There total 5 articles about C₂₁H₁₃F₅N₄O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 852061-71-3
4-fluoro-6-methoxy-5-(trifluoromethyl)pyrimidine

: 1276039-83-8
C₁₅H₁₀F₂N₂O₂

: 1276034-20-8
C₂₁H₁₃F₅N₄O₃

Guidance literature:: With potassium carbonate; In dimethyl sulfoxide; at 80 ℃; for 1h;

Reference yield:

: 394-31-0
2-amino-5-hydroxybenzoic acid

: 1276034-20-8
C₂₁H₁₃F₅N₄O₃

Guidance literature:: Multi-step reaction with 4 steps

1.1: acetic acid / 0.5 h / 20 °C / Inert atmosphere

1.2: 20 °C / Cooling

2.1: ammonium bicarbonate; triethylamine; HATU / N,N-dimethyl-formamide / 20 °C / Inert atmosphere

3.1: trifluoroacetic acid / 1 h / 20 °C / Inert atmosphere

4.1: potassium carbonate / dimethyl sulfoxide / 1 h / 80 °C

With ammonium bicarbonate; potassium carbonate; triethylamine; HATU; trifluoroacetic acid; In acetic acid; dimethyl sulfoxide; N,N-dimethyl-formamide;

Reference yield:

: 1550-35-2
2,4-difluorobenzaldehyde

: 1276034-20-8
C₂₁H₁₃F₅N₄O₃

Guidance literature:: Multi-step reaction with 4 steps

1.1: acetic acid / 0.5 h / 20 °C / Inert atmosphere

1.2: 20 °C / Cooling

2.1: ammonium bicarbonate; triethylamine; HATU / N,N-dimethyl-formamide / 20 °C / Inert atmosphere

3.1: trifluoroacetic acid / 1 h / 20 °C / Inert atmosphere

4.1: potassium carbonate / dimethyl sulfoxide / 1 h / 80 °C

With ammonium bicarbonate; potassium carbonate; triethylamine; HATU; trifluoroacetic acid; In acetic acid; dimethyl sulfoxide; N,N-dimethyl-formamide;