2,4-DIHYDROXY-5-HYDROXYMETHYLPYRIDINE

Base Information

Chemical Name:2,4-DIHYDROXY-5-HYDROXYMETHYLPYRIDINE
CAS No.:143834-60-0
Molecular Formula:C₆H₇NO₃
Molecular Weight:141.126
Hs Code.:
Mol file:143834-60-0.mol

Synonyms:2(1H)-Pyridinone,4-hydroxy-5-(hydroxymethyl);4-Hydroxy-5-(hydroxymethyl)-2(1H)-pyridinone;2,4-Dihydroxy-5-hydroxymethylpyridine;

Suppliers and Price of 2,4-DIHYDROXY-5-HYDROXYMETHYLPYRIDINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2,4-DIHYDROXY-5-HYDROXYMETHYLPYRIDINE 95.00%
5MG
$ 504.06

Total 9 raw suppliers

Chemical Property of 2,4-DIHYDROXY-5-HYDROXYMETHYLPYRIDINE

Chemical Property:

Vapor Pressure:3.75E-15mmHg at 25°C
Refractive Index:1.662
Boiling Point:598.1°Cat760mmHg
PKA:4.50±1.00(Predicted)
Flash Point:315.5°C
PSA：73.58000
Density:1.512g/cm³
LogP:-0.01490

Purity/Quality:

98%Min ^*data from raw suppliers

2,4-DIHYDROXY-5-HYDROXYMETHYLPYRIDINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2,4-DIHYDROXY-5-HYDROXYMETHYLPYRIDINE

There total 3 articles about 2,4-DIHYDROXY-5-HYDROXYMETHYLPYRIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 143834-59-7
2,4-di-(tert.-butyldimethylsilyloxy)-5-hydroxymethyl-pyridine

: 143834-60-0
2,4-dihydroxy-5-hydroxymethyl-pyridine

Guidance literature:: With acetic acid; for 2h; Ambient temperature;
DOI:10.1016/S0040-4020(01)88214-4

Reference yield:

: 6975-44-6
4,6-dihydroxynicotinic acid ethyl ester

: 143834-60-0
2,4-dihydroxy-5-hydroxymethyl-pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: 89 percent / imidazole / dimethylformamide / Ambient temperature

2: 78 percent / LiAlH₄ / diethyl ether / 3 h / -50 - -40 °C

3: 86 percent / 80percent HOAc / 2 h / Ambient temperature

With 1H-imidazole; lithium aluminium tetrahydride; acetic acid; In diethyl ether; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)88214-4

Reference yield:

: 143834-58-6
ethyl 2,4-di-(tert.-butyldimethylsilyloxy)pyridine-5-carboxylate

: 143834-60-0
2,4-dihydroxy-5-hydroxymethyl-pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 78 percent / LiAlH₄ / diethyl ether / 3 h / -50 - -40 °C

2: 86 percent / 80percent HOAc / 2 h / Ambient temperature

With lithium aluminium tetrahydride; acetic acid; In diethyl ether;
DOI:10.1016/S0040-4020(01)88214-4