(3R,4R,5R)-3,4-di-O-benzyl-3,4,5-trihydroxypiperidine

Base Information

Chemical Name:(3R,4R,5R)-3,4-di-O-benzyl-3,4,5-trihydroxypiperidine
CAS No.:177420-27-8
Molecular Formula:C₁₉H₂₃NO₃
Molecular Weight:313.397
Hs Code.:

Synonyms:(3R,4R,5R)-3,4-di-O-benzyl-3,4,5-trihydroxypiperidine

Suppliers and Price of (3R,4R,5R)-3,4-di-O-benzyl-3,4,5-trihydroxypiperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3R,4R,5R)-3,4-di-O-benzyl-3,4,5-trihydroxypiperidine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3R,4R,5R)-3,4-di-O-benzyl-3,4,5-trihydroxypiperidine

There total 11 articles about (3R,4R,5R)-3,4-di-O-benzyl-3,4,5-trihydroxypiperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: (3S,4R,5R)-5-Azidomethyl-3,4-bis-benzyloxy-tetrahydro-furan-2-ol

: 177420-27-8
(3R,4R,5R)-3,4-di-O-benzyl-3,4,5-trihydroxypiperidine

Guidance literature:: With hydrogen; Lindlar's catalyst; In methanol; for 18h; Ambient temperature;
DOI:10.1016/0040-4039(96)00422-4

Reference yield:

: 177567-99-6
1,2,3-tri-O-acetyl-5-azido-5-deoxy-D-arabinofuranose

: 177420-27-8
(3R,4R,5R)-3,4-di-O-benzyl-3,4,5-trihydroxypiperidine

Guidance literature:: Multi-step reaction with 5 steps

1: 84 percent / TMSOTf / CH₂Cl₂ / 3 h / Ambient temperature

2: NaOMe, MeOH / 0.5 h / Ambient temperature

3: 1.) NaH / 1.) DMF, RT, 30 min, 2.) DMF, RT, overnight

4: (NH₄)2Ce(NO₃)6 / H₂O; acetonitrile / 0.08 h / 0 - 5 °C

5: H₂ / Pd-CaCO₃ / methanol / 24 h / Ambient temperature

With methanol; ammonium cerium(IV) nitrate; trimethylsilyl trifluoromethanesulfonate; hydrogen; sodium methylate; sodium hydride; Lindlar's catalyst; In methanol; dichloromethane; water; acetonitrile;
DOI:10.1021/ja973443k