5-[3-{2,6-bis(2,2,2-trifluoroacetylamino)hexanoyl}-1-propynyl]-5'-O-(4,4'-dimethoxytrityl) LNA uridine

Base Information

Chemical Name:5-[3-{2,6-bis(2,2,2-trifluoroacetylamino)hexanoyl}-1-propynyl]-5'-O-(4,4'-dimethoxytrityl) LNA uridine
CAS No.:1275611-26-1
Molecular Formula:C₄₄H₄₃F₆N₅O₁₁
Molecular Weight:931.843
Hs Code.:

Synonyms:5-[3-{2,6-bis(2,2,2-trifluoroacetylamino)hexanoyl}-1-propynyl]-5'-O-(4,4'-dimethoxytrityl) LNA uridine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-[3-{2,6-bis(2,2,2-trifluoroacetylamino)hexanoyl}-1-propynyl]-5'-O-(4,4'-dimethoxytrityl) LNA uridine

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Technology Process of 5-[3-{2,6-bis(2,2,2-trifluoroacetylamino)hexanoyl}-1-propynyl]-5'-O-(4,4'-dimethoxytrityl) LNA uridine

There total 1 articles about 5-[3-{2,6-bis(2,2,2-trifluoroacetylamino)hexanoyl}-1-propynyl]-5'-O-(4,4'-dimethoxytrityl) LNA uridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: C₃₄H₃₃N₃O₈

: 329-53-3
N^α,N^ε-bis(trifluoroacetyl)-L-lysine

: 1275611-26-1
5-[3-{2,6-bis(2,2,2-trifluoroacetylamino)hexanoyl}-1-propynyl]-5'-O-(4,4'-dimethoxytrityl) LNA uridine

Guidance literature:: N^α,N^ε-bis(trifluoroacetyl)-L-lysine; With O-(N-succinimidyl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

C₃₄H₃₃N₃O₈; In N,N-dimethyl-formamide; at 0 - 20 ℃;