1-(7-amino-1H-indol-3-yl)-2-(4-benzoyl-2-methylpiperazin-1-yl)ethane-1,2-dione

Base Information

Chemical Name:1-(7-amino-1H-indol-3-yl)-2-(4-benzoyl-2-methylpiperazin-1-yl)ethane-1,2-dione
CAS No.:1357376-40-9
Molecular Formula:C₂₂H₂₂N₄O₃
Molecular Weight:390.442
Hs Code.:

Synonyms:1-(7-amino-1H-indol-3-yl)-2-(4-benzoyl-2-methylpiperazin-1-yl)ethane-1,2-dione

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-(7-amino-1H-indol-3-yl)-2-(4-benzoyl-2-methylpiperazin-1-yl)ethane-1,2-dione

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Technology Process of 1-(7-amino-1H-indol-3-yl)-2-(4-benzoyl-2-methylpiperazin-1-yl)ethane-1,2-dione

There total 3 articles about 1-(7-amino-1H-indol-3-yl)-2-(4-benzoyl-2-methylpiperazin-1-yl)ethane-1,2-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1357376-37-4
C₂₂H₂₀N₄O₅

: 1357376-40-9
1-(7-amino-1H-indol-3-yl)-2-(4-benzoyl-2-methylpiperazin-1-yl)ethane-1,2-dione

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; at 20 ℃; for 24h; under 2068.65 - 2585.81 Torr;

Reference yield:

: 6960-42-5
7-nitro-1H-indole

: 1357376-40-9
1-(7-amino-1H-indol-3-yl)-2-(4-benzoyl-2-methylpiperazin-1-yl)ethane-1,2-dione

Guidance literature:: Multi-step reaction with 3 steps

1: 24 h

2: N-ethyl-N,N-diisopropylamine / 24 h

3: hydrogen / palladium on activated charcoal / ethanol / 24 h / 20 °C / 2068.65 - 2585.81 Torr

With hydrogen; N-ethyl-N,N-diisopropylamine; palladium on activated charcoal; In ethanol;

Reference yield:

: C₁₀H₅ClN₂O₄

: 1357376-40-9
1-(7-amino-1H-indol-3-yl)-2-(4-benzoyl-2-methylpiperazin-1-yl)ethane-1,2-dione

Guidance literature:: Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine / 24 h

2: hydrogen / palladium on activated charcoal / ethanol / 24 h / 20 °C / 2068.65 - 2585.81 Torr

With hydrogen; N-ethyl-N,N-diisopropylamine; palladium on activated charcoal; In ethanol;