1-benzyl-4-(1-cyclopent-2-enyl-1H-indol-3-yl)-3-(1H-indol-3-yl)-1,5-dihydro-pyrrol-2-one

Base Information

• Chemical Name: 1-benzyl-4-(1-cyclopent-2-enyl-1H-indol-3-yl)-3-(1H-indol-3-yl)-1,5-dihydro-pyrrol-2-one
• CAS No.: 441283-66-5
• Molecular Formula: C₃₂H₂₇N₃O
• Molecular Weight: 469.586

Synonyms:1-benzyl-4-(1-cyclopent-2-enyl-1H-indol-3-yl)-3-(1H-indol-3-yl)-1,5-dihydro-pyrrol-2-one

Chemical Property of 1-benzyl-4-(1-cyclopent-2-enyl-1H-indol-3-yl)-3-(1H-indol-3-yl)-1,5-dihydro-pyrrol-2-one

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Technology Process of 1-benzyl-4-(1-cyclopent-2-enyl-1H-indol-3-yl)-3-(1H-indol-3-yl)-1,5-dihydro-pyrrol-2-one

There total 2 articles about 1-benzyl-4-(1-cyclopent-2-enyl-1H-indol-3-yl)-3-(1H-indol-3-yl)-1,5-dihydro-pyrrol-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

tert-butyl cyclopent-2-en-1-yl carbonate + 1-benzyl-3,4-bis-(1H-indol-3-yl)-1,5-dihydro-pyrrol-2-one → 1-benzyl-4-(1-cyclopent-2-enyl-1H-indol-3-yl)-3-(1H-indol-3-yl)-1,5-dihydro-pyrrol-2-one (441283-66-5)

Guidance literature:

tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; In dichloromethane; at -20 - 20 ℃; for 15h; catalytic alkylation;

DOI:10.1021/ol020046s

Reference yield:

tert-butyl cyclopent-2-en-1-yl carbonate + 1-benzyl-3,4-bis-(1H-indol-3-yl)-1,5-dihydro-pyrrol-2-one → 1-benzyl-4-(1-cyclopent-2-enyl-1H-indol-3-yl)-3-(1H-indol-3-yl)-1,5-dihydro-pyrrol-2-one + 1-benzyl-4-(1-cyclopent-2-enyl-1H-indol-3-yl)-3-(1H-indol-3-yl)-1,5-dihydro-pyrrol-2-one (441283-66-5)

Guidance literature:

With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; (1R,2R)-1,2-bis[(2-diphenylphosphanyl)benzoylamino]cyclohexane; In dichloromethane; at 25 ℃; Further Variations:; Temperatures; Solvents; Product distribution;

DOI:10.1021/ol020046s

Reference yield: 87.0%

1-benzyl-4-(1-cyclopent-2-enyl-1H-indol-3-yl)-3-(1H-indol-3-yl)-1,5-dihydro-pyrrol-2-one (441283-66-5) → C27H21N3OC5H4

Guidance literature:

With toluene-4-sulfonic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In benzene; for 1.5h; Heating;

DOI:10.1021/ol020046s

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