Technology Process of C26H32N4O5
There total 12 articles about C26H32N4O5 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
chloroformic acid ethyl ester; triethylamine;
In
tetrahydrofuran;
at 0 - 25 ℃;
for 16h;
DOI:10.1016/j.bmcl.2010.04.123
- Guidance literature:
-
Multi-step reaction with 8 steps
1.1: n-butyllithium / tetrahydrofuran / -78 - 20 °C / Inert atmosphere
1.2: -78 - 20 °C / Inert atmosphere
2.1: 24 h / 45 °C / Inert atmosphere
2.2: 1.5 h / Inert atmosphere
2.3: 0.5 h / Inert atmosphere
3.1: dihydrogen peroxide; lithium hydroxide monohydrate / water; tetrahydrofuran / 1 h / 0 °C
4.1: 20 - 60 °C
5.1: 4-methyl-morpholine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 12 h / 20 °C
6.1: lithium hydroxide monohydrate / water; tetrahydrofuran / 1 h / 20 °C
7.1: tetrahydrofuran / 1 h / 0 - 20 °C
8.1: ethyl acetate / 12 h / 20 °C
With
4-methyl-morpholine; n-butyllithium; lithium hydroxide monohydrate; dihydrogen peroxide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
tetrahydrofuran; dichloromethane; water; ethyl acetate;
DOI:10.1016/j.ejmech.2014.07.106