Toluene-4-sulfonic acid (3E,5E,7E)-3-((E)-2-cyano-1-methyl-vinyl)-6-methyl-8-(2,6,6-trimethyl-cyclohex-1-enyl)-octa-3,5,7-trienyl ester

Base Information

Chemical Name:Toluene-4-sulfonic acid (3E,5E,7E)-3-((E)-2-cyano-1-methyl-vinyl)-6-methyl-8-(2,6,6-trimethyl-cyclohex-1-enyl)-octa-3,5,7-trienyl ester
CAS No.:144736-18-5
Molecular Formula:C₂₉H₃₇NO₃S
Molecular Weight:479.684
Hs Code.:

Synonyms:Toluene-4-sulfonic acid (3E,5E,7E)-3-((E)-2-cyano-1-methyl-vinyl)-6-methyl-8-(2,6,6-trimethyl-cyclohex-1-enyl)-octa-3,5,7-trienyl ester

Suppliers and Price of Toluene-4-sulfonic acid (3E,5E,7E)-3-((E)-2-cyano-1-methyl-vinyl)-6-methyl-8-(2,6,6-trimethyl-cyclohex-1-enyl)-octa-3,5,7-trienyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Toluene-4-sulfonic acid (3E,5E,7E)-3-((E)-2-cyano-1-methyl-vinyl)-6-methyl-8-(2,6,6-trimethyl-cyclohex-1-enyl)-octa-3,5,7-trienyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Toluene-4-sulfonic acid (3E,5E,7E)-3-((E)-2-cyano-1-methyl-vinyl)-6-methyl-8-(2,6,6-trimethyl-cyclohex-1-enyl)-octa-3,5,7-trienyl ester

There total 6 articles about Toluene-4-sulfonic acid (3E,5E,7E)-3-((E)-2-cyano-1-methyl-vinyl)-6-methyl-8-(2,6,6-trimethyl-cyclohex-1-enyl)-octa-3,5,7-trienyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 3,7-dimethyl-4-(2-hydroxyethyl)-9-(2,6,6-trimethyl-1-cyclohexenyl)-nona-2,4,6,8-tetraenenitrile

: 98-59-9
p-toluenesulfonyl chloride

: 144736-18-5
Toluene-4-sulfonic acid (3E,5E,7E)-3-((E)-2-cyano-1-methyl-vinyl)-6-methyl-8-(2,6,6-trimethyl-cyclohex-1-enyl)-octa-3,5,7-trienyl ester

Guidance literature:: With pyridine; at -15 ℃;
DOI:10.1021/ja00053a023

Reference yield:

: 3917-41-7
(2E,4E)-3-methyl-5-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4-pentadienal

: 144736-18-5
Toluene-4-sulfonic acid (3E,5E,7E)-3-((E)-2-cyano-1-methyl-vinyl)-6-methyl-8-(2,6,6-trimethyl-cyclohex-1-enyl)-octa-3,5,7-trienyl ester

Guidance literature:: Multi-step reaction with 6 steps

1: 1.) NaH / 1.) THF, 0 deg C, 15 min, 2.) THF, 30 min

2: 1.) (CH₃)3SiCl / 1.) THF, -100 deg C, 2.) THF, from -100 deg C to -90 deg C, 15 min

3: 92 percent / 4-dimethylaminopyridine / 2 h / Ambient temperature

4: tetrahydrofuran / 1 h / 20 - 45 °C

5: KOH / methanol / 1 h / -30 - -20 °C

6: 72 percent / pyridine / -15 °C

With pyridine; dmap; potassium hydroxide; chloro-trimethyl-silane; sodium hydride; In tetrahydrofuran; methanol;
DOI:10.1021/ja00053a023

Reference yield:

: 144736-14-1
2-(3-methyl-5-(2,6,6-trimethyl-1-cyclohexenyl)-2,4-pentadienylidene)-γ-butyrolactone

: 144736-18-5
Toluene-4-sulfonic acid (3E,5E,7E)-3-((E)-2-cyano-1-methyl-vinyl)-6-methyl-8-(2,6,6-trimethyl-cyclohex-1-enyl)-octa-3,5,7-trienyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) (CH₃)3SiCl / 1.) THF, -100 deg C, 2.) THF, from -100 deg C to -90 deg C, 15 min

2: 92 percent / 4-dimethylaminopyridine / 2 h / Ambient temperature

3: tetrahydrofuran / 1 h / 20 - 45 °C

4: KOH / methanol / 1 h / -30 - -20 °C

5: 72 percent / pyridine / -15 °C

With pyridine; dmap; potassium hydroxide; chloro-trimethyl-silane; In tetrahydrofuran; methanol;
DOI:10.1021/ja00053a023