methyl 2-deoxy-3-O-(4-methylbenzoyl)-5-O-(4-methoxyphenyl)diphenylmethyl-D-erythro-pentofuranoside

Base Information

• Chemical Name: methyl 2-deoxy-3-O-(4-methylbenzoyl)-5-O-(4-methoxyphenyl)diphenylmethyl-D-erythro-pentofuranoside
• CAS No.: 78137-89-0
• Molecular Formula: C₃₄H₃₄O₆
• Molecular Weight: 538.64
• Mol file: 78137-89-0.mol

Synonyms:methyl 2-deoxy-3-O-(4-methylbenzoyl)-5-O-(4-methoxyphenyl)diphenylmethyl-D-erythro-pentofuranoside

Chemical Property of methyl 2-deoxy-3-O-(4-methylbenzoyl)-5-O-(4-methoxyphenyl)diphenylmethyl-D-erythro-pentofuranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2-deoxy-3-O-(4-methylbenzoyl)-5-O-(4-methoxyphenyl)diphenylmethyl-D-erythro-pentofuranoside

There total 3 articles about methyl 2-deoxy-3-O-(4-methylbenzoyl)-5-O-(4-methoxyphenyl)diphenylmethyl-D-erythro-pentofuranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

4-methyl-benzoyl chloride (874-60-2) + methyl 2-deoxy-5-O-(4-methoxyphenyl)diphenyl-D-methyl-erythro-pento-D-furanoside (105454-47-5) → methyl 2-deoxy-3-O-(4-methylbenzoyl)-5-O-(4-methoxyphenyl)diphenylmethyl-D-erythro-pentofuranoside (78137-89-0)

Guidance literature:

In pyridine; for 18h; Ambient temperature;

DOI:10.1016/S0008-6215(00)85610-4

Reference yield:

mono-4-methoxytrityl chloride (14470-28-1) → methyl 2-deoxy-3-O-(4-methylbenzoyl)-5-O-(4-methoxyphenyl)diphenylmethyl-D-erythro-pentofuranoside (78137-89-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 22 percent / pyridine / 18 h / Ambient temperature

2: 84 percent / pyridine / 18 h / Ambient temperature

In pyridine;

DOI:10.1016/S0008-6215(00)85610-4

Reference yield:

1-O-methyl-2-deoxy-D-ribofuranoside (51255-17-5,51255-18-6,60134-26-1,89577-26-4,96038-80-1,96039-31-5,144301-84-8,144301-85-9) → methyl 2-deoxy-3-O-(4-methylbenzoyl)-5-O-(4-methoxyphenyl)diphenylmethyl-D-erythro-pentofuranoside (78137-89-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 22 percent / pyridine / 18 h / Ambient temperature

2: 84 percent / pyridine / 18 h / Ambient temperature

In pyridine;

DOI:10.1016/S0008-6215(00)85610-4

upstream raw materials:

4-methyl-benzoyl chloride

methyl 2-deoxy-5-O-(4-methoxyphenyl)diphenyl-D-methyl-erythro-pento-D-furanoside

mono-4-methoxytrityl chloride

1-O-methyl-2-deoxy-D-ribofuranoside

Downstream raw materials:

1-<5-O-benzyl-3-O-(4-methylbenzoyl)-2-deoxy-α-D-erythro-pentofuranosyl>-5,6-dihydro-5-N-methyl-s-triazine-2,4-(3H)-dione

1-<5-O-benzyl-3-O-(4-methylbenzoyl)-2-deoxy-β-D-erythro-pentofuranosyl>-5,6-dihydro-5-N-methyl-s-triazine-2,4-(3H)-dione

1-O-acetyl-5-O-benzyl-2-deoxy-3-O-(4-methylbenzoyl)-D-erythro-pentofuranose

methyl 5-O-benzyl-2-deoxy-3-O-(4-methylbenzoyl)-D-erythro-pentofuranoside