Technology Process of methyl 5-(4-methoxyphenyl)pentanoate
There total 11 articles about methyl 5-(4-methoxyphenyl)pentanoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
palladium on activated charcoal; hydrogen;
In
ethanol;
at 20 ℃;
for 10h;
Inert atmosphere;
DOI:10.1016/j.bmc.2014.03.012
- Guidance literature:
-
With
manganese; 3-(trifluoromethyl)pyridine; nickel(II) bromide 2-methoxyethyl ether complex; 1,4-di(diphenylphosphino)-butane; magnesium bromide;
In
dimethyl sulfoxide; acetonitrile;
at 45 ℃;
for 36h;
DOI:10.1039/c8sc00609a
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: sulfuric acid / 3.5 h / Reflux; Inert atmosphere
2.1: diisobutylaluminium hydride / tetrahydrofuran / 2.5 h / -78 °C / Inert atmosphere
3.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.5 h / -78 °C / Inert atmosphere
3.2: 0.33 h / 20 °C / Inert atmosphere
4.1: toluene / 0.33 h / Inert atmosphere; Reflux
5.1: hydrogen; palladium on activated charcoal / ethanol / 10 h / 20 °C / Inert atmosphere
With
oxalyl dichloride; sulfuric acid; palladium on activated charcoal; hydrogen; diisobutylaluminium hydride; dimethyl sulfoxide;
In
tetrahydrofuran; ethanol; dichloromethane; toluene;
4.1: |Wittig Olefination;
DOI:10.1016/j.bmc.2014.03.012
