2-O-acetyl-4,6-O-benzylidene-3-O-(2-naphthylmethyl)-β-D-mannopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalamido-β-D-glucopyranosyl N-phenyl trifluoroacetimidate

Base Information

Chemical Name:2-O-acetyl-4,6-O-benzylidene-3-O-(2-naphthylmethyl)-β-D-mannopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalamido-β-D-glucopyranosyl N-phenyl trifluoroacetimidate
CAS No.:1169693-65-5
Molecular Formula:C₆₂H₅₅F₃N₂O₁₃
Molecular Weight:1093.12
Hs Code.:

2-O-acetyl-4,6-O-benzylidene-3-O-(2-naphthylmethyl)-β-D-mannopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalamido-β-D-glucopyranosyl N-phenyl trifluoroacetimidate

Synonyms:2-O-acetyl-4,6-O-benzylidene-3-O-(2-naphthylmethyl)-β-D-mannopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalamido-β-D-glucopyranosyl N-phenyl trifluoroacetimidate

Suppliers and Price of 2-O-acetyl-4,6-O-benzylidene-3-O-(2-naphthylmethyl)-β-D-mannopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalamido-β-D-glucopyranosyl N-phenyl trifluoroacetimidate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-O-acetyl-4,6-O-benzylidene-3-O-(2-naphthylmethyl)-β-D-mannopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalamido-β-D-glucopyranosyl N-phenyl trifluoroacetimidate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-O-acetyl-4,6-O-benzylidene-3-O-(2-naphthylmethyl)-β-D-mannopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalamido-β-D-glucopyranosyl N-phenyl trifluoroacetimidate

There total 12 articles about 2-O-acetyl-4,6-O-benzylidene-3-O-(2-naphthylmethyl)-β-D-mannopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalamido-β-D-glucopyranosyl N-phenyl trifluoroacetimidate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: dimethylthexylsilyl [4,6-O-benzylidene-2-O-levulenoyl-3-O-(2-methylnaphthyl)-β-D-glucopyranosyl]-(1→4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranoside

: 1169693-65-5
2-O-acetyl-4,6-O-benzylidene-3-O-(2-naphthylmethyl)-β-D-mannopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalamido-β-D-glucopyranosyl N-phenyl trifluoroacetimidate

Guidance literature:: Multi-step reaction with 4 steps

1.1: hydrazinium monoacetate / tetrahydrofuran / 3 h / Inert atmosphere

2.1: trifluoromethylsulfonic anhydride; pyridine / dichloromethane / 1 h / 20 °C / Inert atmosphere

2.2: Inert atmosphere

3.1: pyridine; pyridine hydrogenfluoride / 15 h / Inert atmosphere

4.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane / 0.5 h / Inert atmosphere

With pyridine; trifluoromethylsulfonic anhydride; hydrazinium monoacetate; pyridine hydrogenfluoride; 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; dichloromethane;
DOI:10.1002/anie.202105647

Reference yield:

: dimethylthexylsilyl [4,6-O-benzylidene-3-O-(2-methylnaphthyl)-β-D-glucopyranosyl]-(1→4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranoside

: 1169693-65-5
2-O-acetyl-4,6-O-benzylidene-3-O-(2-naphthylmethyl)-β-D-mannopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalamido-β-D-glucopyranosyl N-phenyl trifluoroacetimidate

Guidance literature:: Multi-step reaction with 3 steps

1.1: trifluoromethylsulfonic anhydride; pyridine / dichloromethane / 1 h / 20 °C / Inert atmosphere

1.2: Inert atmosphere

2.1: pyridine; pyridine hydrogenfluoride / 15 h / Inert atmosphere

3.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane / 0.5 h / Inert atmosphere

With pyridine; trifluoromethylsulfonic anhydride; pyridine hydrogenfluoride; 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane;
DOI:10.1002/anie.202105647

Reference yield:

: ethane 4,6-O-benzylidene-2-O-levulenoyl-3-O-(2-methylnaphthyl)-1-thio-β-D-glucopyranoside

: 1169693-65-5
2-O-acetyl-4,6-O-benzylidene-3-O-(2-naphthylmethyl)-β-D-mannopyranosyl-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalamido-β-D-glucopyranosyl N-phenyl trifluoroacetimidate

Guidance literature:: Multi-step reaction with 5 steps

1.1: N-iodo-succinimide; trifluorormethanesulfonic acid / dichloromethane / -30 °C / Molecular sieve; Inert atmosphere

2.1: hydrazinium monoacetate / tetrahydrofuran / 3 h / Inert atmosphere

3.1: trifluoromethylsulfonic anhydride; pyridine / dichloromethane / 1 h / 20 °C / Inert atmosphere

3.2: Inert atmosphere

4.1: pyridine; pyridine hydrogenfluoride / 15 h / Inert atmosphere

5.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane / 0.5 h / Inert atmosphere

With pyridine; N-iodo-succinimide; trifluorormethanesulfonic acid; trifluoromethylsulfonic anhydride; hydrazinium monoacetate; pyridine hydrogenfluoride; 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; dichloromethane;
DOI:10.1002/anie.202105647