p-methylphenyl 2,3,4,6-tetra-O-acetyl-1-thio-β-D-galactopyranoside

Base Information

• Chemical Name: p-methylphenyl 2,3,4,6-tetra-O-acetyl-1-thio-β-D-galactopyranoside
• CAS No.: 1092843-75-8
• Molecular Formula: C₂₁H₂₆O₉S
• Molecular Weight: 454.498
• Mol file: 1092843-75-8.mol

Synonyms:p-methylphenyl 2,3,4,6-tetra-O-acetyl-1-thio-β-D-galactopyranoside

Chemical Property of p-methylphenyl 2,3,4,6-tetra-O-acetyl-1-thio-β-D-galactopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of p-methylphenyl 2,3,4,6-tetra-O-acetyl-1-thio-β-D-galactopyranoside

There total 4 articles about p-methylphenyl 2,3,4,6-tetra-O-acetyl-1-thio-β-D-galactopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

para-thiocresol (106-45-6) + β-D-galactose peracetate (4163-60-4) → 4-methylphenyl 2,3,4,6-tetra-O-acetyl-1-thio-β-D-galactopyranoside (28244-94-2,28244-99-7,86782-41-4,131488-65-8) + p-methylphenyl 2,3,4,6-tetra-O-acetyl-1-thio-β-D-galactopyranoside (1092843-75-8)

Guidance literature:

With boron trifluoride diethyl etherate; at 20 ℃; for 0.666667h; Ionic liquid;

DOI:10.1080/07328303.2011.605195

Reference yield: 92.0%

D-galactose pentaacetate (25878-60-8) + para-thiocresol (106-45-6) → p-methylphenyl 2,3,4,6-tetra-O-acetyl-1-thio-β-D-galactopyranoside (1092843-75-8)

Guidance literature:

With boron trifluoride diethyl etherate; In dichloromethane; at 0 - 20 ℃;

DOI:10.1016/j.carres.2008.06.020

Reference yield: 63.0%

4-methylphenyl 2,3,4,6-tetra-O-acetyl-1-thio-β-D-galactopyranoside (28244-94-2,28244-99-7,86782-41-4,131488-65-8) → p-methylphenyl 2,3,4,6-tetra-O-acetyl-1-thio-β-D-galactopyranoside (1092843-75-8)

Guidance literature:

With trifluorormethanesulfonic acid; In dichloromethane; at 20 ℃; for 0.5h; Molecular sieve;

DOI:10.1021/acs.joc.1c02171

upstream raw materials:

D-galactose pentaacetate

para-thiocresol

β-D-galactose peracetate

sodium p-thiocresolate

Downstream raw materials:

p-methylphenyl 1-thio-β-D-galactopyranoside

p-methylphenyl [(5-N-acetyl-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-α-D-galacto-2-nonulopyranosyl-1'->2-lactone)]-(2->3)-4,6-di-O-acetyl-1-thio-β-D-galactopyranoside

p-methylphenyl [methyl (5-N-acetyl-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-α-D-galacto-2-nonulopyranosyl)onate]-(2->3)-4,6-di-O-acetyl-1-thio-β-D-galactopyranoside

p-methylphenyl [methyl (5-N-acetyl-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-α-D-galacto-2-nonulopyranosyl)onate]-(2->3)-2,4,6-tri-O-acetyl-1-thio-β-D-galactopyranoside