[3-(2-amino-3H-imidazol-4-yl)phenyl]-3,5-difluorobenzamide hydrochloride

Base Information

Chemical Name:[3-(2-amino-3H-imidazol-4-yl)phenyl]-3,5-difluorobenzamide hydrochloride
CAS No.:1190333-42-6
Molecular Formula:C₁₆H₁₂F₂N₄O*ClH
Molecular Weight:350.755
Hs Code.:

Synonyms:[3-(2-amino-3H-imidazol-4-yl)phenyl]-3,5-difluorobenzamide hydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of [3-(2-amino-3H-imidazol-4-yl)phenyl]-3,5-difluorobenzamide hydrochloride

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Technology Process of [3-(2-amino-3H-imidazol-4-yl)phenyl]-3,5-difluorobenzamide hydrochloride

There total 2 articles about [3-(2-amino-3H-imidazol-4-yl)phenyl]-3,5-difluorobenzamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 1190334-00-9
2-amino-5-[3-(3,5-difluorobenzoylamino)phenyl]imidazole-1-carboxylic acid tert-butyl ester

: 1190333-42-6
[3-(2-amino-3H-imidazol-4-yl)phenyl]-3,5-difluorobenzamide hydrochloride

Guidance literature:: 2-amino-5-[3-(3,5-difluorobenzoylamino)phenyl]imidazole-1-carboxylic acid tert-butyl ester; With trifluoroacetic acid; In dichloromethane; at 0 - 20 ℃;

With hydrogenchloride; In diethyl ether; dichloromethane;
DOI:10.1016/j.bmcl.2010.04.042