7,8-cis-1α,25-dihydroxyvitamin D₃

Base Information

• Chemical Name: 7,8-cis-1α,25-dihydroxyvitamin D₃
• CAS No.: 157809-60-4
• Molecular Formula: C₂₇H₄₄O₃
• Molecular Weight: 416.645
• Mol file: 157809-60-4.mol

Synonyms:7,8-cis-1α,25-dihydroxyvitamin D₃

Chemical Property of 7,8-cis-1α,25-dihydroxyvitamin D₃

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 7,8-cis-1α,25-dihydroxyvitamin D₃

There total 1 articles about 7,8-cis-1α,25-dihydroxyvitamin D₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(1S,3R,6S)-1,3,25-trihydroxy-9,10-secocholesta-5(10),6,7-triene → 1α-25-dihydroxy-cis-isotachysterol + 7,8-cis-1α,25-dihydroxyvitamin D3 (157809-60-4)

Guidance literature:

With (C₁₀H₈)(CO)3Cr; In acetone; at 40 ℃; for 4h; Yields of byproduct given;

Reference yield: 67.0%

7,8-cis-1α,25-dihydroxyvitamin D3 (157809-60-4) → calcitriol (32222-06-3)

Guidance literature:

With 9-acetylanthracene; In d⁽⁴⁾-methanol; for 1.5h; Irradiation;

Reference yield: 43.0%

7,8-cis-1α,25-dihydroxyvitamin D3 (157809-60-4) → 1α-25-dihydroxy-cis-isotachysterol

Guidance literature:

In acetone; at 57 ℃; for 18.5h;

Downstream raw materials:

calcitriol

(1S),3(R)-9,10-secocholesta-5(E),7(E),10⁽¹⁹⁾-triene-1,3,25-triol

Refernces