N-<5(S)-benzamido-4-oxo-6-phenylhexanoyl>-2-phosphonopyrrolidine

Base Information

Chemical Name:N-<5(S)-benzamido-4-oxo-6-phenylhexanoyl>-2-phosphonopyrrolidine
CAS No.:96792-01-7
Molecular Formula:C₂₃H₂₇N₂O₆P
Molecular Weight:458.451
Hs Code.:

Synonyms:N-<5(S)-benzamido-4-oxo-6-phenylhexanoyl>-2-phosphonopyrrolidine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-<5(S)-benzamido-4-oxo-6-phenylhexanoyl>-2-phosphonopyrrolidine

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Technology Process of N-<5(S)-benzamido-4-oxo-6-phenylhexanoyl>-2-phosphonopyrrolidine

There total 2 articles about N-<5(S)-benzamido-4-oxo-6-phenylhexanoyl>-2-phosphonopyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 96792-07-3
N-<5(S)-benzamido-4-oxo-6-phenylhexanoyl>-2-(diethoxyphosphinyl)pyrrolidine

: 96792-01-7
N-<5(S)-benzamido-4-oxo-6-phenylhexanoyl>-2-phosphonopyrrolidine

Guidance literature:: With trimethylsilyl bromide; In dichloromethane; for 64.5h; Ambient temperature;
DOI:10.1021/jm00146a015

Reference yield:

: 74075-31-3,83356-17-6
(5S)-5-[(N-benzoyl)amino]-4-oxo-6-phenyl-hexanoic acid

: 96792-01-7
N-<5(S)-benzamido-4-oxo-6-phenylhexanoyl>-2-phosphonopyrrolidine

Guidance literature:: Multi-step reaction with 2 steps

1: 66.4 percent / dicyclohexylcarbodiimide / CH₂Cl₂; dimethylformamide / 40 h / Ambient temperature

2: 55 percent / bromotrimethylsilane / CH₂Cl₂ / 64.5 h / Ambient temperature

With trimethylsilyl bromide; dicyclohexyl-carbodiimide; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm00146a015