(E)-tert-butyldimethyl(6-(prop-1-enyl)benzo[d][1,3]dioxol-5-yloxy)silane

Base Information

• Chemical Name: (E)-tert-butyldimethyl(6-(prop-1-enyl)benzo[d][1,3]dioxol-5-yloxy)silane
• CAS No.: 1189161-31-6
• Molecular Formula: C₁₆H₂₄O₃Si
• Molecular Weight: 292.45
• Mol file: 1189161-31-6.mol

Synonyms:(E)-tert-butyldimethyl(6-(prop-1-enyl)benzo[d][1,3]dioxol-5-yloxy)silane

Chemical Property of (E)-tert-butyldimethyl(6-(prop-1-enyl)benzo[d][1,3]dioxol-5-yloxy)silane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-tert-butyldimethyl(6-(prop-1-enyl)benzo[d][1,3]dioxol-5-yloxy)silane

There total 2 articles about (E)-tert-butyldimethyl(6-(prop-1-enyl)benzo[d][1,3]dioxol-5-yloxy)silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

trans-2-propenyl bromide (590-15-8) + tert-butyldimethyl(6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d][1,3]dioxol-5-yloxy)silane (1189161-30-5) → (E)-tert-butyldimethyl(6-(prop-1-enyl)benzo[d][1,3]dioxol-5-yloxy)silane (1189161-31-6)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; potassium tert-butylate; In toluene; at 20 ℃; for 2h; Inert atmosphere;

DOI:10.1021/ol9017326

Reference yield: 46.0%

trans-2-propenyl bromide (590-15-8) + tert-butyl(6-iodobenzo[d][1,3]dioxol-5-yloxy)dimethylsilane (1189161-29-2) → (E)-tert-butyldimethyl(6-(prop-1-enyl)benzo[d][1,3]dioxol-5-yloxy)silane (1189161-31-6)

Guidance literature:

trans-2-propenyl bromide; With tert.-butyl lithium; In toluene; Inert atmosphere;

With zinc(II) chloride; In tetrahydrofuran; Inert atmosphere;

tert-butyl(6-iodobenzo[d][1,3]dioxol-5-yloxy)dimethylsilane; With tri-tert-butyl phosphine; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In N,N-dimethyl-formamide; at 80 ℃; Inert atmosphere;

DOI:10.1021/ol9017326

upstream raw materials:

trans-2-propenyl bromide

tert-butyl(6-iodobenzo[d][1,3]dioxol-5-yloxy)dimethylsilane

tert-butyldimethyl(6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d][1,3]dioxol-5-yloxy)silane