(2-AMINO-1-PHENYL-ETHYL)-CARBAMIC ACID TERT-BUTYL ESTER

Base Information

• Chemical Name: (2-AMINO-1-PHENYL-ETHYL)-CARBAMIC ACID TERT-BUTYL ESTER
• CAS No.: 142910-85-8
• Molecular Formula: C₁₃H₂₀N₂O₂
• Molecular Weight: 236.314
• Hs Code.: 2924299090
• Mol file: 142910-85-8.mol

Synonyms:Carbamicacid, (2-amino-1-phenylethyl)-, 1,1-dimethylethyl ester (9CI);1,1-Dimethylethyl (2-amino-1-phenylethyl)carbamate

Chemical Property of (2-AMINO-1-PHENYL-ETHYL)-CARBAMIC ACID TERT-BUTYL ESTER

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 85-90°C
• Refractive Index: 1.524
• Boiling Point: 372.2°Cat760mmHg
• PKA: 11?+-.0.46(Predicted)
• Flash Point: 178.9°C
• PSA: 64.35000
• Density: 1.066g/cm³
• LogP: 3.30230
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

97% ^*data from raw suppliers

α-(Boc-amino)phenethylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22-37/38-41
• Safety Statements: 26-39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: Reactant for:Preparation of γ-lactams from carboxylic acids and amines via UDC (Ugi/De-BOC/Cyclize) strategy using isonitriles

Technology Process of (2-AMINO-1-PHENYL-ETHYL)-CARBAMIC ACID TERT-BUTYL ESTER

There total 56 articles about (2-AMINO-1-PHENYL-ETHYL)-CARBAMIC ACID TERT-BUTYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

(R)-N-(tert-butoxycarbonyl)phenylglycinol (67341-01-9,117049-14-6,138457-46-2,102089-74-7) → (R)-(2-amino-1-phenyl-ethyl)-carbamic acid tert-butyl ester (137102-65-9,142910-85-8)

Guidance literature:

With phthalimide; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; at 20 ℃; for 6h; Cooling with ice;

Reference yield: 99.0%

(S)-(+)-1-<(butoxycarbonyl)amino>-1-phenylethyl azide (137102-29-5) → (S)-N1-tert-butoxycarbonyl-1-phenyl-1,2-ethanediamine (137102-30-8,142910-85-8)

Guidance literature:

(S)-(+)-1-<(butoxycarbonyl)amino>-1-phenylethyl azide; With triphenylphosphine; In tetrahydrofuran; for 8h; Reflux;

With water; In tetrahydrofuran; for 16h; Reflux;

DOI:10.1039/c2ob25693b

Reference yield: 96.0%

(R)-(-)-1-<(butoxycarbonyl)amino>-1-phenylethyl azide (134557-76-9) → (R)-(2-amino-1-phenyl-ethyl)-carbamic acid tert-butyl ester (137102-65-9,142910-85-8)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 10h;

DOI:10.1016/j.bmcl.2005.05.038

upstream raw materials:

Phenylglycinol

di-tert-butyl dicarbonate

tert-butyl 2-hydroxy-1-phenylethylcarbamate

benzyl 3-(1,3-dioxoisoindolin-2-yl)-2-phenylpropanoate

Downstream raw materials:

{2-[3-(2-fluoro-3-methoxy-phenyl)-ureido]-1-phenyl-ethyl}-carbamic acid tert-butyl ester

C₃₀H₃₂N₄O₂S₂

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 142910-85-8 (2-AMINO-1-PHENYL-ETHYL)-CARBAMIC ACID TERT-BUTYL ESTER

Send

Send

Metric Ton KG G Pound L ML

Send

Send