1,3-dimethyl-6-<3-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-3-oxopropyl>lumazine

Base Information

• Chemical Name: 1,3-dimethyl-6-<3-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-3-oxopropyl>lumazine
• CAS No.: 121617-38-7
• Molecular Formula: C₃₇H₃₂N₄O₁₀
• Molecular Weight: 692.682
• Mol file: 121617-38-7.mol

Synonyms:1,3-dimethyl-6-<3-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-3-oxopropyl>lumazine

Chemical Property of 1,3-dimethyl-6-<3-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-3-oxopropyl>lumazine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,3-dimethyl-6-<3-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-3-oxopropyl>lumazine

There total 2 articles about 1,3-dimethyl-6-<3-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-3-oxopropyl>lumazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 29.0%

4,5-Diamino-1,3-dimethyluracil (5440-00-6) + 6-hydroxy-6-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)pyran-3<2H,6H>-one (121701-32-4) → 1,3-dimethyl-6-<3-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-3-oxopropyl>lumazine (121617-38-7)

Guidance literature:

With diethyl ether; boron trifluoride; In acetonitrile; for 24h; Ambient temperature;

DOI:10.1021/jo00277a033

Reference yield: 16.0%

4,5-Diamino-1,3-dimethyluracil (5440-00-6) + 6-hydroxy-6-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)pyran-3<2H,6H>-one (121701-32-4) → 1,3-dimethyl-7-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)lumazine (121617-37-6) + 1,3-dimethyl-6-<3-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-3-oxopropyl>lumazine (121617-38-7) + 6,8-dimethyl-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)pyrrolo<1,2-f>pteridine-7,9-dione (121617-39-8)

Guidance literature:

In toluene; at 80 ℃; for 5h;

DOI:10.1021/jo00277a033

Reference yield: 58.0%

1,3-dimethyl-6-<3-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-3-oxopropyl>lumazine (121617-38-7) → Benzoic acid 5-[3-(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pteridin-6-yl)-propionyl]-furan-2-ylmethyl ester (121617-40-1)

Guidance literature:

With toluene-4-sulfonic acid; In chloroform; for 6h; Heating;

DOI:10.1021/jo00277a033

upstream raw materials:

4,5-Diamino-1,3-dimethyluracil

6-hydroxy-6-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)pyran-3<2H,6H>-one

Downstream raw materials:

Benzoic acid 5-[3-(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pteridin-6-yl)-propionyl]-furan-2-ylmethyl ester