(+)-2-(tert-butyloxycarbonylamino)-3-methoxy-N-(benzyloxycarbonyl)morphinan

Base Information

Chemical Name:(+)-2-(tert-butyloxycarbonylamino)-3-methoxy-N-(benzyloxycarbonyl)morphinan
CAS No.:1262870-09-6
Molecular Formula:C₃₀H₃₈N₂O₅
Molecular Weight:506.642
Hs Code.:

Synonyms:(+)-2-(tert-butyloxycarbonylamino)-3-methoxy-N-(benzyloxycarbonyl)morphinan

Suppliers and Price of (+)-2-(tert-butyloxycarbonylamino)-3-methoxy-N-(benzyloxycarbonyl)morphinan

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (+)-2-(tert-butyloxycarbonylamino)-3-methoxy-N-(benzyloxycarbonyl)morphinan

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (+)-2-(tert-butyloxycarbonylamino)-3-methoxy-N-(benzyloxycarbonyl)morphinan

There total 6 articles about (+)-2-(tert-butyloxycarbonylamino)-3-methoxy-N-(benzyloxycarbonyl)morphinan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 1262870-06-3
(+)-2-amino-3-methoxy-N-(benzyloxycarbonyl)morphinan

: 1262870-09-6
(+)-2-(tert-butyloxycarbonylamino)-3-methoxy-N-(benzyloxycarbonyl)morphinan

Guidance literature:: di-tert-butyl dicarbonate; (+)-2-amino-3-methoxy-N-(benzyloxycarbonyl)morphinan; In tetrahydrofuran; at 20 ℃;

With sodium hydrogencarbonate; In tetrahydrofuran;

Reference yield:

: 15676-23-0
(+)-3-Hydroxymorphinan

: 1262870-09-6
(+)-2-(tert-butyloxycarbonylamino)-3-methoxy-N-(benzyloxycarbonyl)morphinan

Guidance literature:: Multi-step reaction with 5 steps

1: nitric acid; formic acid / water / 0 - 20 °C

2: sodium hydroxide / 1,4-dioxane / 0 - 20 °C

3: potassium carbonate / acetone / 20 °C

4: hydrazine hydrate / Raney nickel / water; methanol / 2 h / 20 °C

5: tetrahydrofuran / 20 °C

With formic acid; nitric acid; potassium carbonate; hydrazine hydrate; sodium hydroxide; Raney nickel; In tetrahydrofuran; 1,4-dioxane; methanol; water; acetone;

Reference yield:

: (+)-3-hydroxymorphinan hydrobromide

: 1262870-09-6
(+)-2-(tert-butyloxycarbonylamino)-3-methoxy-N-(benzyloxycarbonyl)morphinan

Guidance literature:: Multi-step reaction with 6 steps

1: sodium hydroxide / 1,4-dioxane; water / 0.5 h / 0 - 20 °C

2: nitric acid; formic acid / water / 0 - 20 °C

3: sodium hydroxide / 1,4-dioxane / 0 - 20 °C

4: potassium carbonate / acetone / 20 °C

5: hydrazine hydrate / Raney nickel / water; methanol / 2 h / 20 °C

6: tetrahydrofuran / 20 °C

With formic acid; nitric acid; potassium carbonate; hydrazine hydrate; sodium hydroxide; Raney nickel; In tetrahydrofuran; 1,4-dioxane; methanol; water; acetone;