2-deuteriobenzothiophene

Base Information

• Chemical Name: 2-deuteriobenzothiophene
• CAS No.: 63724-94-7
• Molecular Formula: C₈H₆S
• Molecular Weight: 135.194
• Mol file: 63724-94-7.mol

Synonyms:2-deuteriobenzothiophene

Chemical Property of 2-deuteriobenzothiophene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-deuteriobenzothiophene

There total 3 articles about 2-deuteriobenzothiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

iodobenzene (591-50-4) + Benzo[b]thiophene (95-15-8,11095-43-5) → 2-deuteriobenzothiophene (63724-94-7) + 2-phenylbenzo[b]thiophene (1207-95-0)

Guidance literature:

With copper(l) iodide; 1,10-Phenanthroline; tert-butyl alcohol-d; lithium tert-butoxide; In 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; at 125 ℃; for 1h; Inert atmosphere;

DOI:10.1021/ja805688p

Reference yield:

4-tolyl iodide (624-31-7) + Benzo[b]thiophene (95-15-8,11095-43-5) → 2-deuteriobenzothiophene (63724-94-7) + 2-(4-methylphenyl)benzo[b]thiophene (25664-47-5)

Guidance literature:

With copper(l) iodide; 1,10-Phenanthroline; tert-butyl alcohol-d; lithium tert-butoxide; In 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; at 125 ℃; for 1h; Inert atmosphere;

DOI:10.1021/ja805688p

Reference yield:

4-Iodobenzotrifluoride (455-13-0) + Benzo[b]thiophene (95-15-8,11095-43-5) → 2-deuteriobenzothiophene (63724-94-7) + 2-[4-(trifluoromethyl)phenyl]-benzo[b]thiophene

Guidance literature:

With copper(l) iodide; 1,10-Phenanthroline; tert-butyl alcohol-d; lithium tert-butoxide; In 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; at 125 ℃; for 1h; Inert atmosphere;

DOI:10.1021/ja805688p

upstream raw materials:

iodobenzene

Benzo[b]thiophene

4-tolyl iodide

4-Iodobenzotrifluoride

Downstream raw materials:

2-(4-methoxyphenyl)benzo[b]thiophene

2-[4-(1,1-dimethylethyl)phenyl]benzo[b]thiophene

2,2'-bibenzo[b]thiophene

2-(2-methylphenyl)-1-benzothiophene