7-chloro-9-(4-nitro-phenyl)-4H-3,10,10a-triaza-benzo[f]azulene-2-carboxylic acid ethyl ester

Base Information

• Chemical Name: 7-chloro-9-(4-nitro-phenyl)-4H-3,10,10a-triaza-benzo[f]azulene-2-carboxylic acid ethyl ester
• CAS No.: 220445-43-2
• Molecular Formula: C₂₀H₁₅ClN₄O₄
• Molecular Weight: 410.816

Synonyms:7-chloro-9-(4-nitro-phenyl)-4H-3,10,10a-triaza-benzo[f]azulene-2-carboxylic acid ethyl ester

Chemical Property of 7-chloro-9-(4-nitro-phenyl)-4H-3,10,10a-triaza-benzo[f]azulene-2-carboxylic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 7-chloro-9-(4-nitro-phenyl)-4H-3,10,10a-triaza-benzo[f]azulene-2-carboxylic acid ethyl ester

There total 4 articles about 7-chloro-9-(4-nitro-phenyl)-4H-3,10,10a-triaza-benzo[f]azulene-2-carboxylic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

7-chloro-2-hydroxy-9-(4-nitro-phenyl)-2,4-dihydro-1H-3,10,10a-triaza-benzo[f]azulene-2-carboxylic acid ethyl ester (869309-08-0) → 7-chloro-9-(4-nitro-phenyl)-4H-3,10,10a-triaza-benzo[f]azulene-2-carboxylic acid ethyl ester (220445-43-2) + 3-[8-chloro-1-(4-nitro-phenyl)-4-oxo-4,5-dihydro-benzo[d][1,2]diazepin-3-yl]-2-oxo-propionic acid ethyl ester

Guidance literature:

With toluene-4-sulfonic acid; In ethanol; chloroform;

DOI:10.1016/j.bmcl.2005.07.080

Reference yield:

8-chloro-1-(4-nitro-phenyl)-5H-benzo[d][1,2]diazepin-4-ylamine (869309-07-9) → 7-chloro-9-(4-nitro-phenyl)-4H-3,10,10a-triaza-benzo[f]azulene-2-carboxylic acid ethyl ester (220445-43-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 65 percent / K₂CO₃ / dimethylformamide / 20 °C

2: 58 percent / p-toluenesulfonic acid / ethanol; CHCl₃

With potassium carbonate; toluene-4-sulfonic acid; In ethanol; chloroform; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2005.07.080

Reference yield:

ethyl Bromopyruvate (70-23-5) → 7-chloro-9-(4-nitro-phenyl)-4H-3,10,10a-triaza-benzo[f]azulene-2-carboxylic acid ethyl ester (220445-43-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 65 percent / K₂CO₃ / dimethylformamide / 20 °C

2: 58 percent / p-toluenesulfonic acid / ethanol; CHCl₃

With potassium carbonate; toluene-4-sulfonic acid; In ethanol; chloroform; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2005.07.080

upstream raw materials:

7-chloro-2-hydroxy-9-(4-nitro-phenyl)-2,4-dihydro-1H-3,10,10a-triaza-benzo[f]azulene-2-carboxylic acid ethyl ester

8-chloro-1-(4-nitro-phenyl)-5H-benzo[d][1,2]diazepin-4-ylamine

ethyl Bromopyruvate

8-chloro-1-(4-nitrophenyl)-3,5-dihydro-4H-2,3-benzodiazepin-4-thione

Downstream raw materials:

9-(4-amino-phenyl)-7-chloro-4H-3,10,10a-triaza-benzo[f]azulene-2-carboxylic acid

[9-(4-amino-phenyl)-7-chloro-4H-3,10,10a-triaza-benzo[f]azulen-2-yl]-methanol

9-(4-amino-phenyl)-7-chloro-4H-3,10,10a-triaza-benzo[f]azulene-2-carboxylic acid ethyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 220445-43-2 7-chloro-9-(4-nitro-phenyl)-4H-3,10,10a-triaza-benzo[f]azulene-2-carboxylic acid ethyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send