tert-butyl N-[(2S,3S)-3-hydroxybutan-2-yl]carbamate

Base Information

Chemical Name:tert-butyl N-[(2S,3S)-3-hydroxybutan-2-yl]carbamate
CAS No.:157394-45-1
Molecular Formula:C₉H₁₉NO₃
Molecular Weight:189.255
Hs Code.:
European Community (EC) Number:966-611-8
Nikkaji Number:J1.432.500J
Mol file:157394-45-1.mol

Synonyms:157394-45-1;tert-butyl N-[(2S,3S)-3-hydroxybutan-2-yl]carbamate;Carbamic acid, [(1S,2S)-2-hydroxy-1-methylpropyl]-, 1,1-dimethylethyl ester;EN300-7548033;tert-Butyl ((2S,3S)-3-hydroxybutan-2-yl)carbamate

Suppliers and Price of tert-butyl N-[(2S,3S)-3-hydroxybutan-2-yl]carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of tert-butyl N-[(2S,3S)-3-hydroxybutan-2-yl]carbamate

Chemical Property:

Boiling Point:286.5±23.0 °C(Predicted)
PKA:12.41±0.46(Predicted)
PSA：58.56000
Density:1.008±0.06 g/cm3(Predicted)
LogP:1.67130
XLogP3:1.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:189.13649347
Heavy Atom Count:13
Complexity:174

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(C)O)NC(=O)OC(C)(C)C
Isomeric SMILES:C[C@@H]([C@H](C)O)NC(=O)OC(C)(C)C

Technology Process of tert-butyl N-[(2S,3S)-3-hydroxybutan-2-yl]carbamate

There total 6 articles about tert-butyl N-[(2S,3S)-3-hydroxybutan-2-yl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 310450-40-9
(2R,3S,R_S)-N-(tert-butoxycarbonyl)-3-amino-1-(p-tolylsulfinyl)-2-butanol

: 157394-45-1
(2S,3S)-N-(tert-butoxycarbonyl)-3-amino-2-butanol

Guidance literature:: With nickel; In methanol; at 20 ℃; for 1h;
DOI:10.1016/S0957-4166(00)00264-0

Reference yield: 70.0%

: 917-54-4
methyllithium

: 79069-50-4
Boc-Ala-H

: 157394-45-1
(2S,3S)-N-(tert-butoxycarbonyl)-3-amino-2-butanol

Guidance literature:: With copper(I) bromide dimethylsulfide complex; In diethyl ether; hexane; at -55 ℃; for 3h;
DOI:10.1016/S0040-4039(00)73024-3

Reference yield:

: Boc-D-Thr(OBzl)ψCH₃

: 157394-45-1
(2S,3S)-N-(tert-butoxycarbonyl)-3-amino-2-butanol

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In chloroform; for 12h; under 760.051 Torr;
DOI:10.1002/anie.201608955