2,2-dimethyl-propionic acid [4-(2-chloro-4,6-dimethoxyphenyl)thieno[2,3-d]pyrimidin-2-yl]amide

Base Information

Chemical Name:2,2-dimethyl-propionic acid [4-(2-chloro-4,6-dimethoxyphenyl)thieno[2,3-d]pyrimidin-2-yl]amide
CAS No.:1028332-23-1
Molecular Formula:C₁₉H₂₀ClN₃O₃S
Molecular Weight:405.905
Hs Code.:

Synonyms:2,2-dimethyl-propionic acid [4-(2-chloro-4,6-dimethoxyphenyl)thieno[2,3-d]pyrimidin-2-yl]amide

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Chemical Property of 2,2-dimethyl-propionic acid [4-(2-chloro-4,6-dimethoxyphenyl)thieno[2,3-d]pyrimidin-2-yl]amide

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Technology Process of 2,2-dimethyl-propionic acid [4-(2-chloro-4,6-dimethoxyphenyl)thieno[2,3-d]pyrimidin-2-yl]amide

There total 1 articles about 2,2-dimethyl-propionic acid [4-(2-chloro-4,6-dimethoxyphenyl)thieno[2,3-d]pyrimidin-2-yl]amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.5%

: 1028332-10-6
4-chloro-2-pivaloylaminothieno[2,3-d]pyrimidine

: 1028332-16-2
2-(2-chloro-4,6-dimethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

: 1028332-23-1
2,2-dimethyl-propionic acid [4-(2-chloro-4,6-dimethoxyphenyl)thieno[2,3-d]pyrimidin-2-yl]amide

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In 1,4-dioxane; water; at 85 ℃; for 12h;

Reference yield: 57.0%

: 1028332-23-1
2,2-dimethyl-propionic acid [4-(2-chloro-4,6-dimethoxyphenyl)thieno[2,3-d]pyrimidin-2-yl]amide

: 1028331-64-7
4-(2-chloro-4,6-dimethoxyphenyl)thieno[2,3-d]pyrimidin-2-amine

Guidance literature:: 2,2-dimethyl-propionic acid [4-(2-chloro-4,6-dimethoxyphenyl)thieno[2,3-d]pyrimidin-2-yl]amide; With sodium hydroxide; In ethanol; water; at 90 ℃; for 12h;

In water; Aqueous acetate buffer;