trans-p-tert-butyl-1,4-dihydrobenzoic acid

Base Information

• Chemical Name: trans-p-tert-butyl-1,4-dihydrobenzoic acid
• CAS No.: 103241-25-4
• Molecular Formula: C₁₁H₁₆O₂
• Molecular Weight: 180.247
• Mol file: 103241-25-4.mol

Synonyms:trans-p-tert-butyl-1,4-dihydrobenzoic acid

Chemical Property of trans-p-tert-butyl-1,4-dihydrobenzoic acid

Chemical Property:

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Technology Process of trans-p-tert-butyl-1,4-dihydrobenzoic acid

There total 1 articles about trans-p-tert-butyl-1,4-dihydrobenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

4-(1,1-dimethylethyl)benzoic acid (98-73-7) → trans-p-tert-butyl-1,4-dihydrobenzoic acid (103241-25-4)

Guidance literature:

With ammonia; sodium; In tetrahydrofuran; at -33 ℃; for 0.333333h;

DOI:10.1021/jo00360a010

upstream raw materials:

4-(1,1-dimethylethyl)benzoic acid