(S)-N-(4-Aminomethyl-phenyl)-2-(N',N''-dicyclohexyl-guanidino)-3-naphthalen-2-yl-propionamide

Base Information

Chemical Name:(S)-N-(4-Aminomethyl-phenyl)-2-(N',N''-dicyclohexyl-guanidino)-3-naphthalen-2-yl-propionamide
CAS No.:195716-34-8
Molecular Formula:C₃₃H₄₃N₅O
Molecular Weight:525.737
Hs Code.:

Synonyms:(S)-N-(4-Aminomethyl-phenyl)-2-(N',N''-dicyclohexyl-guanidino)-3-naphthalen-2-yl-propionamide

Suppliers and Price of (S)-N-(4-Aminomethyl-phenyl)-2-(N',N''-dicyclohexyl-guanidino)-3-naphthalen-2-yl-propionamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-N-(4-Aminomethyl-phenyl)-2-(N',N''-dicyclohexyl-guanidino)-3-naphthalen-2-yl-propionamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-N-(4-Aminomethyl-phenyl)-2-(N',N''-dicyclohexyl-guanidino)-3-naphthalen-2-yl-propionamide

There total 5 articles about (S)-N-(4-Aminomethyl-phenyl)-2-(N',N''-dicyclohexyl-guanidino)-3-naphthalen-2-yl-propionamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4403-71-8
(4-aminomethyl)aniline

: 195716-34-8
(S)-N-(4-Aminomethyl-phenyl)-2-(N',N''-dicyclohexyl-guanidino)-3-naphthalen-2-yl-propionamide

Guidance literature:: Multi-step reaction with 5 steps

1: tetra(n-butyl)ammonium hydrogensulfate; sodium hydrogencarbonate / dichloromethane

2: benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide / N,N-dimethyl-formamide

3: hydrogenchloride / ethyl acetate

4: triethylamine; dicyclohexyl-carbodiimide / tert-butyl alcohol / 80 °C

5: hydrazine hydrate / methanol

With hydrogenchloride; tetra(n-butyl)ammonium hydrogensulfate; sodium hydrogencarbonate; benzotriazol-1-ol; hydrazine hydrate; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; triethylamine; dicyclohexyl-carbodiimide; In methanol; dichloromethane; ethyl acetate; N,N-dimethyl-formamide; tert-butyl alcohol;
DOI:10.1016/S0960-894X(97)00328-4

Reference yield:

: 195718-13-9
(S)-2-(N',N''-Dicyclohexyl-guanidino)-N-[4-(1,3-dioxo-1,3-dihydro-isoindol-2-ylmethyl)-phenyl]-3-naphthalen-2-yl-propionamide

: 195716-34-8
(S)-N-(4-Aminomethyl-phenyl)-2-(N',N''-dicyclohexyl-guanidino)-3-naphthalen-2-yl-propionamide

Guidance literature:: With hydrazine hydrate; In methanol;
DOI:10.1016/S0960-894X(97)00328-4

Reference yield:

: 100880-61-3
2-(4-amino-benzyl)-isoindole-1,3-dione

: 195716-34-8
(S)-N-(4-Aminomethyl-phenyl)-2-(N',N''-dicyclohexyl-guanidino)-3-naphthalen-2-yl-propionamide

Guidance literature:: Multi-step reaction with 4 steps

1: benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide / N,N-dimethyl-formamide

2: hydrogenchloride / ethyl acetate

3: triethylamine; dicyclohexyl-carbodiimide / tert-butyl alcohol / 80 °C

4: hydrazine hydrate / methanol

With hydrogenchloride; benzotriazol-1-ol; hydrazine hydrate; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; triethylamine; dicyclohexyl-carbodiimide; In methanol; ethyl acetate; N,N-dimethyl-formamide; tert-butyl alcohol;
DOI:10.1016/S0960-894X(97)00328-4