3-((4-fluorophenyl)(hydroxy)methylene)-1-methyl-1H-benzo[g]indol-2(3H)-one

Base Information

Chemical Name:3-((4-fluorophenyl)(hydroxy)methylene)-1-methyl-1H-benzo[g]indol-2(3H)-one
CAS No.:1384559-68-5
Molecular Formula:C₂₀H₁₄FNO₂
Molecular Weight:319.335
Hs Code.:

Synonyms:3-((4-fluorophenyl)(hydroxy)methylene)-1-methyl-1H-benzo[g]indol-2(3H)-one

Suppliers and Price of 3-((4-fluorophenyl)(hydroxy)methylene)-1-methyl-1H-benzo[g]indol-2(3H)-one

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-((4-fluorophenyl)(hydroxy)methylene)-1-methyl-1H-benzo[g]indol-2(3H)-one

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Technology Process of 3-((4-fluorophenyl)(hydroxy)methylene)-1-methyl-1H-benzo[g]indol-2(3H)-one

There total 3 articles about 3-((4-fluorophenyl)(hydroxy)methylene)-1-methyl-1H-benzo[g]indol-2(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 1384559-45-8
3-(4-fluorophenyl)-N-methyl-N-(naphthalen-1-yl)prop-2-ynamide

: 1384559-68-5
3-((4-fluorophenyl)(hydroxy)methylene)-1-methyl-1H-benzo[g]indol-2(3H)-one

Guidance literature:: With 2-bromopyridine-N-oxide; tris(2,4-di-tert-butylphenyl)phosphite gold(I) chloride; silver(I) triflimide; In 1,2-dichloro-ethane; at 20 ℃; Inert atmosphere;
DOI:10.1039/c2cc31972a

Reference yield:

: C₁₉H₁₂FNO

: 1384559-68-5
3-((4-fluorophenyl)(hydroxy)methylene)-1-methyl-1H-benzo[g]indol-2(3H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / Inert atmosphere

2: 2-bromopyridine-N-oxide; tris(2,4-di-tert-butylphenyl)phosphite gold(I) chloride; silver(I) triflimide / 1,2-dichloro-ethane / 20 °C / Inert atmosphere

With 2-bromopyridine-N-oxide; tris(2,4-di-tert-butylphenyl)phosphite gold(I) chloride; sodium hydride; silver(I) triflimide; In tetrahydrofuran; 1,2-dichloro-ethane; mineral oil;
DOI:10.1039/c2cc31972a

Reference yield:

: 706-06-9
3-(4-flurophenyl)prop-2-ynoic acid

: 1384559-68-5
3-((4-fluorophenyl)(hydroxy)methylene)-1-methyl-1H-benzo[g]indol-2(3H)-one

Guidance literature:: Multi-step reaction with 3 steps

1: dmap; dicyclohexyl-carbodiimide / dichloromethane / 12 h / -20 - 20 °C / Inert atmosphere

2: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / Inert atmosphere

3: 2-bromopyridine-N-oxide; tris(2,4-di-tert-butylphenyl)phosphite gold(I) chloride; silver(I) triflimide / 1,2-dichloro-ethane / 20 °C / Inert atmosphere

With 2-bromopyridine-N-oxide; dmap; tris(2,4-di-tert-butylphenyl)phosphite gold(I) chloride; sodium hydride; dicyclohexyl-carbodiimide; silver(I) triflimide; In tetrahydrofuran; dichloromethane; 1,2-dichloro-ethane; mineral oil;
DOI:10.1039/c2cc31972a