N-[2-chloro-4-(2-furyl)-6-(4-methoxybenzylamino)pyrimidin-5-ylamino]formamide

Base Information

• Chemical Name: N-[2-chloro-4-(2-furyl)-6-(4-methoxybenzylamino)pyrimidin-5-ylamino]formamide
• CAS No.: 1173900-25-8
• Molecular Formula: C₁₇H₁₅ClN₄O₃
• Molecular Weight: 358.784

Synonyms:N-[2-chloro-4-(2-furyl)-6-(4-methoxybenzylamino)pyrimidin-5-ylamino]formamide

Chemical Property of N-[2-chloro-4-(2-furyl)-6-(4-methoxybenzylamino)pyrimidin-5-ylamino]formamide

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Technology Process of N-[2-chloro-4-(2-furyl)-6-(4-methoxybenzylamino)pyrimidin-5-ylamino]formamide

There total 1 articles about N-[2-chloro-4-(2-furyl)-6-(4-methoxybenzylamino)pyrimidin-5-ylamino]formamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

2-chloro-6-(2-furyl)-9-[(4-methoxyphenyl)methyl]-9H-purine (850792-12-0) → N-[2-chloro-4-(2-furyl)-6-(4-methoxybenzylamino)pyrimidin-5-ylamino]formamide (1173900-25-8)

Guidance literature:

With tetra(n-butyl)ammonium hydroxide; In tetrahydrofuran; water; at 20 ℃; for 1h;

DOI:10.1016/j.bmcl.2009.04.082

Reference yield:

N-[2-chloro-4-(2-furyl)-6-(4-methoxybenzylamino)pyrimidin-5-ylamino]formamide (1173900-25-8) → 2-chloro-6-(2-furyl)-9-[(4-methoxyphenyl)methyl]-9H-purine (850792-12-0)

Guidance literature:

In d⁽⁴⁾-methanol; for 600h;

DOI:10.1016/j.bmc.2010.04.035

upstream raw materials:

2-chloro-6-(2-furyl)-9-[(4-methoxyphenyl)methyl]-9H-purine

Downstream raw materials:

2-chloro-6-(2-furyl)-9-[(4-methoxyphenyl)methyl]-9H-purine

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