3-{1-[5-chloro-2-(2-ethyl-butoxy)-benzyl]-5-methyl-1H-pyrazol-3-yl}-propionic methyl ester

Base Information

Chemical Name:3-{1-[5-chloro-2-(2-ethyl-butoxy)-benzyl]-5-methyl-1H-pyrazol-3-yl}-propionic methyl ester
CAS No.:1354060-49-3
Molecular Formula:C₂₁H₂₉ClN₂O₃
Molecular Weight:392.926
Hs Code.:

Synonyms:3-{1-[5-chloro-2-(2-ethyl-butoxy)-benzyl]-5-methyl-1H-pyrazol-3-yl}-propionic methyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-{1-[5-chloro-2-(2-ethyl-butoxy)-benzyl]-5-methyl-1H-pyrazol-3-yl}-propionic methyl ester

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Technology Process of 3-{1-[5-chloro-2-(2-ethyl-butoxy)-benzyl]-5-methyl-1H-pyrazol-3-yl}-propionic methyl ester

There total 2 articles about 3-{1-[5-chloro-2-(2-ethyl-butoxy)-benzyl]-5-methyl-1H-pyrazol-3-yl}-propionic methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 4737-41-1
3-(chloromethyl)pentane

: 1354060-48-2
3-[1-(5-chloro-2-hydroxy-benzyl)-5-methyl-1H-pyrazol-3-yl]-propionic acid methyl ester

: 1354060-49-3
3-{1-[5-chloro-2-(2-ethyl-butoxy)-benzyl]-5-methyl-1H-pyrazol-3-yl}-propionic methyl ester

Guidance literature:: With tetra-(n-butyl)ammonium iodide; potassium carbonate; In N,N-dimethyl-formamide; at 150 ℃; Microwave irradiation;

Reference yield:

: 913572-54-0
1-({5-chloro-2-[(phenylmethyl)oxy]phenyl}methyl)-5-methyl-1H-pyrazole-3-carbaldehyde

: 1354060-49-3
3-{1-[5-chloro-2-(2-ethyl-butoxy)-benzyl]-5-methyl-1H-pyrazol-3-yl}-propionic methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: tetrahydrofuran / 70 h / 20 °C

2: hydrogenchloride; hydrogen / platinum(IV) oxide / water; acetic acid / 16 h / 20 °C

3: potassium carbonate; tetra-(n-butyl)ammonium iodide / N,N-dimethyl-formamide / 150 °C / Microwave irradiation

With hydrogenchloride; hydrogen; tetra-(n-butyl)ammonium iodide; potassium carbonate; platinum(IV) oxide; In tetrahydrofuran; water; acetic acid; N,N-dimethyl-formamide;